Evidence-based treatment and quality of life in heart failure.

OBJECTIVES: To explore whether prescription of evidence-based drug therapy is associated with better quality of life (QoL) in patients with heart failure (HF). METHODS: Patients (n = 62) were recruited in the outpatient clinic of Groningen University Hospital. Inclusion criteria were previous diagno...

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Publicado en:Journal of Evaluation in Clinical Practice Vol. 12; no. 3; pp. 334 - 341
Autores principales: Dobre D, van Jaarsveld CHm, Ranchor AV, Arnold R, de Jongste MJl, Haaijer Ruskamp FM
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Jun2006
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2006
      vid: 12
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      pub: Wiley-Blackwell
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        2009334866
        10.1111/j.1365-2753.2006.00564.x
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        atl: Evidence-based treatment and quality of life in heart failure.
      aug:
        au:
          Dobre D
          van Jaarsveld CHm
          Ranchor AV
          Arnold R
          de Jongste MJl
          Haaijer Ruskamp FM
        affil: Northern Centre for Health Care Research, Department of Health Sciences, University of Groningen, The Netherlands. d.dobre@med.rug.nl
      sug:
        subj:
          Heart Failure Drug Therapy
          Medical Practice, Evidence-Based
          Outcome Assessment
          Practice Guidelines
          Quality of Life
          Academic Medical Centers
          Adrenergic beta-Antagonists Therapeutic Use
          Adult
          Aged
          Aged, 80 and Over
          Angiotensin-Converting Enzyme Inhibitors Therapeutic Use
          Chi Square Test
          Clinical Assessment Tools
          Cross Sectional Studies
          Data Analysis Software
          Diuretics Therapeutic Use
          Drug Therapy, Combination
          Female
          Male
          Middle Age
          Netherlands
          Pearson's Correlation Coefficient
          Spironolactone Therapeutic Use
          Step-Wise Multiple Regression
          T-Tests
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: OBJECTIVES: To explore whether prescription of evidence-based drug therapy is associated with better quality of life (QoL) in patients with heart failure (HF). METHODS: Patients (n = 62) were recruited in the outpatient clinic of Groningen University Hospital. Inclusion criteria were previous diagnosis of HF, age 40-80 years; ejection fraction of less than 45%, free from other serious disease (such as cancer) and psychiatric problems in the last year. QoL was assessed with the RAND 36-item health survey questionnaire, on five scales: physical functioning, mental health, social functioning, vitality and general health perception. Medication prescribed for 1 to 6 months before the QoL assessment was classified as either evidence-based treatment or under-treatment, according to the 2001 European guidelines on optimal HF treatment. The study had a cross-sectional design. RESULTS: QoL did not differ significantly between evidence-based and under-treated patients, unadjusted or after adjustment for significant patient imbalances. CONCLUSIONS: Conventional step-up medication approach in HF may have a positive impact on survival or morbidity, but it seems not beneficial in relation to QoL. Other interventions should be designed to improve QoL of patients with HF.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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