An office-based serological test for detection of current Helicobacter pylori infection: is it useful?
Objective: To compare the accuracy of a new office-based serological test for the detection of current Helicobacter pylori infection with gastric histopathology.Methods: An office-based serological test for detection of current H. pylori infection was performed in 92 consecutive patients with dyspep...
| Publicado en: | European Journal of Gastroenterology & Hepatology Vol. 18; no. 1; pp. 85 - 89 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Jan2006
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106225577&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106225577 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0954691X 8CE jtl: European Journal of Gastroenterology & Hepatology issn: 0954691X maglogo: N pubinfo: dt: Jan2006 vid: 18 iid: 1 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 106225577 106225577 NLM16357625 2009378674 10.1097/00042737-200601000-00015 NLM16357625 106225577 ppf: 85 ppct: 4 formats: tig: atl: An office-based serological test for detection of current Helicobacter pylori infection: is it useful? aug: au: Mumtaz K Abid S Yakoob J Abbas Z Hamid S Islam M Shah HA Jafri W Mumtaz, Khalid Abid, Shahab Yakoob, Javed Abbas, Zaigham Hamid, Saeed Islam, M Shah, Hasnain A Jafri, Wasim affil: Section of Gastroenterology, Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan sug: subj: Diagnosis, Laboratory Methods Helicobacter Infections Diagnosis Recombinant Proteins Diagnostic Use Serologic Tests Methods Adult Biopsy Breath Tests Confidence Intervals Data Analysis Software Descriptive Statistics Dyspepsia Microbiology Feces Analysis Female Gastroscopy Helicobacter Infections Immunology Helicobacter Infections Physiopathology Helicobacter Infections Symptoms Helicobacter Pylori Male Middle Age Outpatient Service Predictive Value of Tests Reagent Kits, Diagnostic Sensitivity and Specificity Stomach Pathology Urease Analysis Human Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Objective: To compare the accuracy of a new office-based serological test for the detection of current Helicobacter pylori infection with gastric histopathology.Methods: An office-based serological test for detection of current H. pylori infection was performed in 92 consecutive patients with dyspeptic symptoms. The result of this test was compared blindly with the rapid urease test and histopathology for H. pylori on gastric biopsies. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of this test were calculated against the histopathology.Results: Among 92 patients, H. pylori was detected by histopathology and rapid urease test in 61 (66%) and 56 (60%) patients, respectively. Meanwhile the serological test diagnosed current H. pylori infection in 55 patients (59%). On comparison against the histology, the sensitivity and specificity of this new serological test was 85 and 90%, respectively. The positive predictive value and negative predictive value of this test were 94 and 76%, and the accuracy was 87% in this study.Conclusion: The specificity and sensitivity of the serological test was found comparable with histopathology in the diagnosis of current H. pylori infection. This test is a useful tool for rapid diagnosis of H. pylori in out patients' setting. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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