Improvement of bacteria detection by flow cytometry (BDFC)

Since bacterial infection of the recipient has become the most frequent infection risk in transfusion medicine, suitable methods for bacteria detection in blood components are of great interest. Platelet concentrates are currently in the focus of attention as they are stored under temperature condit...

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Publicado en:Journal of Laboratory Medicine / Laboratoriums Medizin Vol. 30; no. 6; pp. 394 - 402
Autores principales: Wahl A, Karo O, Nicol S, Brachert J, Lambrecht B, Spengler H, Nauwelaers F, Schmidt M, Müller TH, Montag T
Formato: research tables/charts Journal Article
Publicado: De Gruyter 2006 Nov-Dec
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2006 Nov-Dec
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        atl: Improvement of bacteria detection by flow cytometry (BDFC)
      aug:
        au:
          Wahl A
          Karo O
          Nicol S
          Brachert J
          Lambrecht B
          Spengler H
          Nauwelaers F
          Schmidt M
          Müller TH
          Montag T
        affil: Paul Ehrlich Institute, Langen, Germany
      sug:
        subj:
          Bacterial Contamination Prevention and Control
          Blood Platelets Analysis
          Flow Cytometry
          Platelet Transfusion Adverse Effects
          Bacteria
          Experimental Studies
          In Vitro Studies
          Microbial Culture and Sensitivity Tests
          Human
      ab: Since bacterial infection of the recipient has become the most frequent infection risk in transfusion medicine, suitable methods for bacteria detection in blood components are of great interest. Platelet concentrates are currently in the focus of attention as they are stored under temperature conditions, which enable the multiplication of most bacteria species contaminating blood donations. Rapid methods for bacteria detection allow testing immediately before transfusion in a bedside-like manner. This approach would overcome the sampling error observed in early sampling combined with culturing of bacteria and would at least prevent the transfusion of highly contaminated blood components leading to acute septic shock or even death of the patient.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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