Digestibility of resistant starch containing preparations using two in vitro models.

BACKGROUND: Resistant starch (RS) is known for potential health benefits in the human colon. To investigate these positive effects it is important to be able to predict the amount, and the structure of starch reaching the large intestine. AIM OF THE STUDY: The aim of this study was to compare two di...

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Publicado en:European Journal of Nutrition Vol. 45; no. 8; pp. 445 - 454
Autores principales: Fässler C, Arrigoni E, Venema K, Hafner V, Brouns F, Amadò R
Formato: research tables/charts Journal Article
Publicado: Springer Nature Dec2006
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: European Journal of Nutrition
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      dt: Dec2006
      vid: 45
      iid: 8
      pid: 237
      pub: Springer Nature
      place: New York, New York
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        2009480610
        10.1007/s00394-006-0618-7
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        atl: Digestibility of resistant starch containing preparations using two in vitro models.
      aug:
        au:
          Fässler C
          Arrigoni E
          Venema K
          Hafner V
          Brouns F
          Amadò R
        affil: Institute of Food Science and Nutrition, ETH Zurich, LFO D28 Schmelzbergstr. 9, 8092, Zürich, Switzerland, eva.arrigoni@ilw.agrl.ethz.ch.
      sug:
        subj:
          Digestion
          Glucans Metabolism
          Models, Biological
          Calorimetry
          Data Analysis Software
          Descriptive Statistics
          Feces Analysis
          Funding Source
          Ileostomy
          In Vitro Studies
          One-Way Analysis of Variance
          Post Hoc Analysis
          Human
      ab: BACKGROUND: Resistant starch (RS) is known for potential health benefits in the human colon. To investigate these positive effects it is important to be able to predict the amount, and the structure of starch reaching the large intestine. AIM OF THE STUDY: The aim of this study was to compare two different in vitro models simulating the digestibility of two RS containing preparations. METHODS: The substrates, high amylose maize (HAM) containing RS type 2, and retrograded long chain tapioca maltodextrins (RTmd) containing RS type 3 were in vitro digested using a batch and a dynamic model, respectively. Both preparations were characterized before and after digestion by using X-Ray and DSC, and by measuring their total starch, RS and protein contents. RESULTS: Using both digestion models, 60-61 g/100 g of RTmd turned out to be indigestible, which is very well in accordance with 59 g/100 g found in vivo after feeding RTmd to ileostomy patients. In contrast, dynamic and batch in vitro digestion experiments using HAM as a substrate led to 58 g/100 g and 66 g/100 g RS recovery. The degradability of HAM is more affected by differences in experimental parameters compared to RTmd. The main variations between the two in vitro digestion methods are the enzyme preparations used, incubation times and mechanical stress exerted on the substrate. However, for both preparations dynamically digested fractions led to lower amounts of analytically RS and a lower crystallinity. CONCLUSIONS: The two in vitro digestion methods used attacked the starch molecules differently, which influenced starch digestibility of HAM but not of RTmd.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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