Acupuncture for knee osteoarthritis -- a randomised trial using a novel sham...This trial was originally published as: Bermam B et al. Effectiveness of acupuncture as an adjunctive therapy in osteoarthritis of the knee. Ann Intern Med 2004;141:901-910. It is reproduced with permission of the publishers.

Background Evidence on the efficacy of acupuncture for reducing the pain and dysfunction of osteoarthritis is equivocal. Objective To determine whether acupuncture provides greater pain relief and improved function compared with sham acupuncture or education in patients with osteoarthritis of the kn...

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Publicado en:Acupuncture in Medicine Vol. 24; pp. 7 - 15
Autores principales: Manheimer E, Lim B, Lao L, Berman B
Formato: clinical trial research tables/charts Journal Article
Publicado: Sage Publications Inc. Dec2006 Supplement
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2006 Supplement
      vid: 24
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Acupuncture for knee osteoarthritis -- a randomised trial using a novel sham...This trial was originally published as: Bermam B et al. Effectiveness of acupuncture as an adjunctive therapy in osteoarthritis of the knee. Ann Intern Med 2004;141:901-910. It is reproduced with permission of the publishers.
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        au:
          Manheimer E
          Lim B
          Lao L
          Berman B
        affil: Research Associate, Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore; bberman@compmed.umm.edu
      sug:
        subj:
          Acupuncture
          Osteoarthritis, Knee Therapy
          Acupuncture Points
          Aged
          Alternative Therapies
          Chi Square Test
          Clinical Assessment Tools
          Confidence Intervals
          Data Analysis Software
          Descriptive Statistics
          Double-Blind Studies
          Female
          Funding Source
          Human
          Male
          Middle Age
          One-Way Analysis of Variance
          Osteoarthritis, Knee Physiopathology
          Pain Therapy
          Patient Education
          Power Analysis
          Prospective Studies
          Random Assignment
          Regression
          Short Form-36 Health Survey (SF-36)
          Treatment Outcomes
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Background Evidence on the efficacy of acupuncture for reducing the pain and dysfunction of osteoarthritis is equivocal. Objective To determine whether acupuncture provides greater pain relief and improved function compared with sham acupuncture or education in patients with osteoarthritis of the knee. Design Randomised, controlled trial. Setting Two outpatient clinics (an integrative medicine facility and a rheumatology facility) located in academic teaching hospitals and one clinical trials facility. Patients 570 patients with osteoarthritis of the knee (mean age [±SD], 65.5 ± 8.4 years). Intervention 23 true acupuncture sessions over 26 weeks. Controls received 6 two-hour sessions over 12 weeks or 23 sham acupuncture sessions over 26 weeks. Measurements Primary outcomes were changes in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and function scores at 8 and 26 weeks. Secondary outcomes were patient global assessment, 6-minute walk distance, and physical health scores of the 36-Item Short-Form Health Survey (SF-36). Results Participants in the true acupuncture group experienced greater improvement in WOMAC function scores than the sham acupuncture group at 8 weeks (mean difference, -2.9 [95% CI, -5.0 to -0.81; P=0.01) but not in WOMAC pain score (mean difference, -0.5 [CI, -1.2 to 0.21; P=0. 18) or the patient global assessment (mean difference, 0.16 [CI, -0.02 to 0.341; P> 0.2). At 26 weeks, the true acupuncture group experienced significantly greater improvement than the sham group in the WOMAC function score (mean difference, -2.5 [CI, -4.7 to -0.4]; P=0.01), WOMAC pain score (mean difference, -0.87 [Cl, -1.58 to -0.16]; P=0.003), and patient global assessment (mean difference, 0.26 [CI, 0.07 to 0.45]; P=0.02). Limitations At 26 weeks, 43% of the participants in the education group and 25% in each of the true and sham acupuncture groups were not available for analysis. Conclusions Acupuncture seems to provide improvement in function and pain relief as an adjunctive therapy for osteoarthritis of the knee when compared with credible sham acupuncture and education control groups.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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