Determinants for the adoption of angiotensin II receptor blockers by general practitioners.

Results of studies conducted 10-20 years ago show the prominence of commercial information sources in the adoption process of new drugs. Over the past decade, there has been a growing emphasis on practicing evidence-based medicine in drug prescribing. This raises the question whether professional in...

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Publicado en:Social Science & Medicine Vol. 63; no. 11; pp. 2890 - 2899
Autores principales: Greving JP, Denig P, van der Veen WJ, Beltman FW, Sturkenboom MCJ, Haaijer-Ruskamp FM
Formato: research tables/charts Journal Article
Publicado: Pergamon Press - An Imprint of Elsevier Science Dec2006
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2006
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      pub: Pergamon Press - An Imprint of Elsevier Science
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        10.1016/j.socscimed.2006.07.019
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        atl: Determinants for the adoption of angiotensin II receptor blockers by general practitioners.
      aug:
        au:
          Greving JP
          Denig P
          van der Veen WJ
          Beltman FW
          Sturkenboom MCJ
          Haaijer-Ruskamp FM
        affil: Department of Clinical Pharmacology, University Medical Center Groningen, The Netherlands.
      sug:
        subj:
          Angiotensin II Type I Receptor Blockers Therapeutic Use
          Diffusion of Innovation
          Hypertension Drug Therapy
          Physicians, Family
          Adult
          Aged
          Decision Making, Clinical
          Drug Utilization
          Family Practice
          Female
          Funding Source
          Male
          Middle Age
          National Health Programs Netherlands
          Netherlands
          Prescribing Patterns
          Retrospective Design
          Surveys
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Results of studies conducted 10-20 years ago show the prominence of commercial information sources in the adoption process of new drugs. Over the past decade, there has been a growing emphasis on practicing evidence-based medicine in drug prescribing. This raises the question whether professional information sources currently counterbalance the influence of commercial information sources in the adoption process. The aim of this study was to identify determinants influencing the adoption of a new drug class, the angiotensin II receptor blockers (ARBs), by general practitioners (GPs) in The Netherlands. A retrospective study was conducted to assess prevalent ARB prescribing for hypertensive patients using the Integrated Primary Care Information (IPCI) database. We conducted a survey among all GPs who participated in the IPCI project in 2003 to assess their exposure to commercial and professional information sources, perceived benefits and risks of ARBs, perceived influences of the professional network, and general characteristics. Multilevel logistic regression was applied to identify determinants of ARB adoption while adjusting for patient characteristics. Data were obtained from 70 GPs and 9470 treated hypertensive patients. A total of 1093 patients received ARBs (12%). GPs who reported frequent use of commercial information sources were more likely to prescribe ARBs routinely in preference to other antihypertensives, whereas GPs who used a prescribing decision support system and those who were involved in pharmacotherapy education were less likely to prescribe ARBs. Other factors that were associated with higher levels of ARB adoption included a more positive perception of ARBs regarding their effectiveness in lowering blood pressure, and working in single-handed practices or in rural areas. Aside from determinants related to the patient population, adoption of a new drug class among Dutch GPs is still determined more by their reliance on promotional information than by their use of professional information sources.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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