A case of pyoderma gangrenosum successfully treated with intravenous immune globulin.
Pyoderma gangrenosum is a neutrophilic dermatosis that may be idiopathic or associated with an underlying disease. It is the result of an exaggerated response to specific and non-specific stimuli. First-line treatment is with a steroid, usually prednisone. In this case report, a 25-year-old man pres...
| Published in: | World Wide Wounds pp. 7p - 8 |
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| Main Authors: | , , , , , , |
| Format: | case study pictorial tables/charts Journal Article |
| Published: |
Surgical Materials Testing Laboratory
2007 Jan
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106286681&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106286681 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13692607 Z04 jtl: World Wide Wounds issn: 13692607 maglogo: N pubinfo: dt: 2007 Jan pid: 20562 pub: Surgical Materials Testing Laboratory artinfo: ui: 106286681 106286681 2009536185 106286681 ppf: 7p ppct: 1 formats: tig: atl: A case of pyoderma gangrenosum successfully treated with intravenous immune globulin. aug: au: Carlesimo M Cantisani C Mari E La Pietra M Rossi A Li VW Calvieri S affil: Department of Dermatology and Plastic Surgery, University La Sapienza, Rome, Italy sug: subj: Immunoglobulins, Intravenous Therapeutic Use Pyoderma Gangrenosum Drug Therapy Adult Drug Administration Schedule Immunoglobulins, Intravenous Administration and Dosage Immunoglobulins, Intravenous Pharmacodynamics Male Prednisone Administration and Dosage Pyoderma Gangrenosum Pathology Skin Transplantation Treatment Failure Treatment Outcomes Adult: 19-44 years Male ab: Pyoderma gangrenosum is a neutrophilic dermatosis that may be idiopathic or associated with an underlying disease. It is the result of an exaggerated response to specific and non-specific stimuli. First-line treatment is with a steroid, usually prednisone. In this case report, a 25-year-old man presented with an ulcerated lesion that had appeared spontaneously one year previously. He was treated with prednisone, but this was ineffective. Treatment with intravenous immune globulin (IVIG), however, proved successful. IVIG contains a broad range of antibodies that act against bacterial and viral antigens and is used to treat inflammatory and autoimmune diseases. Its use is therefore recommended for consideration in cases of pyoderma gangrenosum that are steroid resistant. pubtype: Periodical doctype: case study pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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