What is the optimal clinical technique for measurement of left ventricular volume after myocardial infarction? A comparative study of 3-dimensional echocardiography, single photon emission computed tomography, and cardiac magnetic resonance imaging.

BACKGROUND: Left ventricular (LV) volumes have important prognostic implications, but are commonly underestimated. We sought accuracy and reproducibility of LV volume measurement by live 3-dimensional (3D) echocardiography (3DE) and TI-201 single photon emission computed tomography (SPECT), compared...

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Publicado en:Journal of the American Society of Echocardiography Vol. 19; no. 2; pp. 192 - 202
Autores principales: Chan J, Jenkins C, Khafagi F, Du L, Marwick TH
Formato: diagnostic images research tables/charts Journal Article
Publicado: Elsevier B.V. 2006 Feb
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2006 Feb
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      pub: Elsevier B.V.
      place: New York, New York
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        10.1016/j.echo.2005.08.020
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        atl: What is the optimal clinical technique for measurement of left ventricular volume after myocardial infarction? A comparative study of 3-dimensional echocardiography, single photon emission computed tomography, and cardiac magnetic resonance imaging.
      aug:
        au:
          Chan J
          Jenkins C
          Khafagi F
          Du L
          Marwick TH
        affil: University of Queensland
      sug:
        subj:
          Echocardiography, Three-Dimensional
          Heart Ventricle, Left Physiology
          Magnetic Resonance Imaging
          Tomography, Emission-Computed, Single-Photon
          Comparative Studies
          Data Analysis Software
          Data Analysis, Statistical
          Descriptive Statistics
          Female
          Intrarater Reliability
          Male
          Middle Age
          P-Value
          Pearson's Correlation Coefficient
          Human
          Middle Aged: 45-64 years
          Female
          Male
      ab: BACKGROUND: Left ventricular (LV) volumes have important prognostic implications, but are commonly underestimated. We sought accuracy and reproducibility of LV volume measurement by live 3-dimensional (3D) echocardiography (3DE) and TI-201 single photon emission computed tomography (SPECT), compared with cardiac magnetic resonance imaging (MRI). METHODS: In all, 30 patients (age 62 +/- 9 years, 23 men) underwent LV volume assessment with 3DE, SPECT, and cardiac MRI after myocardial infarction. LV volumes were measured using a semiautomated border detection algorithm for 3DE, gated SPECT software for SPECT, and a 3D display for MRI. Results of 3DE and SPECT volumes were compared with MRI as the standard of reference. RESULTS: The 3DE volumes showed excellent correlation with cardiac MRI (end-diastolic volume [EDV], r = 0.90, P = .001; end-systolic volume [ESV], r = 0.94, P = .001), as did SPECT (EDV, r = 0.89, P = .001; ESV, r = 0.95, P = .001). However, both 3DE and SPECT underestimated LV volumes. The mean MRI EDV was 179 +/- 56 mL compared with 3DE (mean difference, -10 +/- 26 mL, P = .04) and SPECT (mean difference, -58 +/- 28 mL, P < .001). There was a significant difference between SPECT EDV and 3DE (mean difference, -48 +/- 31 mL, P < .001). The mean MRI ESV was 96 +/- 54 mL and this was underestimated by SPECT (mean difference, -22 +/- 19 mL, P < .001), but not by 3DE (mean difference, -0.9 +/- 19 mL, P = not significant). ESV was also underestimated when SPECT was compared with 3DE (mean difference, -22 +/- 27 mL, P < .001). The results of 3DE were reproducible with excellent intraobserver (ESV, r = 0.98, -2 +/- 6 mL; EDV, r = 0.98, -1 +/- 6 mL, P = .001) and interobserver (ESV, r = 0.97, -2 +/- 6 mL; EDV, r = 0.95, -3 +/- 10 mL, P = .001) correlation. CONCLUSION: We have shown that 3DE is accurate and reproducible for the measurement of LV volumes for risk assessment in chronic ischemic heart disease and dilated cardiomyopathy. Furthermore, 3DE is more accurate than TI-201 SPECT with less underestimation of LV volumes.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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