Initial experience in the use of integrated electroanatomic mapping with three-dimensional MR/CT images to guide catheter ablation of atrial fibrillation.

INTRODUCTION: No prior studies have reported the use of integrated electroanatomic mapping with preacquired magnetic resonance/computed tomographic (MR/CT) images to guide catheter ablation of atrial fibrillation (AF) in a series of patients. METHODS AND RESULTS: Sixteen consecutive patients with dr...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 17; no. 5; pp. 459 - 467
Autores principales: Dong J, Dickfeld T, Dalal D, Cheema A, Vasamreddy CR, Henrikson CA, Marine JE, Halperin HR, Berger RD, Lima JAC, Bluemke DA, Calkins H
Formato: pictorial research Journal Article
Publicado: Wiley-Blackwell May2006
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2006
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      pub: Wiley-Blackwell
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        atl: Initial experience in the use of integrated electroanatomic mapping with three-dimensional MR/CT images to guide catheter ablation of atrial fibrillation.
      aug:
        au:
          Dong J
          Dickfeld T
          Dalal D
          Cheema A
          Vasamreddy CR
          Henrikson CA
          Marine JE
          Halperin HR
          Berger RD
          Lima JAC
          Bluemke DA
          Calkins H
        affil: Johns Hopkins Hospital, Carnegie 592, 600 N Wolfe Street, Baltimore, MD 21287-0409; jdong4@jhmi.edu
      sug:
        subj:
          Atrial Fibrillation Therapy
          Catheter Ablation Methods
          Magnetic Resonance Imaging Methods
          Tomography, X-Ray Computed Methods
          Descriptive Statistics
          Electrophysiology
          Female
          Fisher's Exact Test
          Heart Atrium Anatomy and Histology
          Male
          Middle Age
          Pulmonary Veins Anatomy and Histology
          Radiographic Image Interpretation, Computer-Assisted
          T-Tests
          Human
          Middle Aged: 45-64 years
          Female
          Male
      ab: INTRODUCTION: No prior studies have reported the use of integrated electroanatomic mapping with preacquired magnetic resonance/computed tomographic (MR/CT) images to guide catheter ablation of atrial fibrillation (AF) in a series of patients. METHODS AND RESULTS: Sixteen consecutive patients with drug-refractory AF underwent catheter ablation under the guidance of a three-dimensional (3D) electroanatomic mapping system (Carto, Biosense Webster, Inc., Diamond Bar, CA, USA). Gadolinium-enhanced MR (n = 8) or contrast-enhanced high-resolution CT (n = 8) imaging was performed within 1 day prior to the ablation procedures. Using a novel software package (CartoMerge, Biosense Webster, Inc.), the left atrium (LA) with pulmonary veins (PVs) was segmented and extracted for image registration. The segmented 3D MR/CT LA reconstruction was accurately registered to the real-time mapping space with a combination of landmark registration and surface registration. The registered 3D MR/CT LA reconstruction was successfully used to guide deployment of RF applications encircling the PVs. Upon completion of the circumferential lesions around the PVs, 32% of the PVs were electrically isolated. Guided by a circular mapping catheter, the remaining PVs were disconnected from the LA using a segmental approach. The distance between the surface of the registered 3D MR/CT LA reconstruction and multiple electroanatomic map points was 3.05 +/- 0.41 mm. No complications were observed. CONCLUSIONS: Three-dimensional MR/CT images can be successfully extracted and registered to anatomically guided clinical AF ablations. The display of detailed and accurate anatomic information during the procedure enables tailored RF ablation to individual PV and LA anatomy.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        Journal Article
      ougenre: Article
    language: English
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