Ileocolic free flap reconstruction, concomitant chemotherapy and radiotherapy and assessment of speech and swallowing function during management of advanced cancer of the larynx and hypopharynx: preliminary report.

CONCLUSION: The new technique of ileocolic free flap reconstruction provides a better quality of life in terms of swallowing and speech for patients who have undergone laryngopharyngectomy with concomitant chemotherapy and radiotherapy (CCRT). OBJECTIVES: To compare and contrast the swallowing and s...

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Publicado en:Acta Oto-Laryngologica Vol. 125; no. 6; pp. 642 - 647
Autores principales: Leu Y, Hsiao H, Chang Y, Yang C, Lee J, Chen Y
Formato: pictorial research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jun2005
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Taylor & Francis Ltd
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        atl: Ileocolic free flap reconstruction, concomitant chemotherapy and radiotherapy and assessment of speech and swallowing function during management of advanced cancer of the larynx and hypopharynx: preliminary report.
      aug:
        au:
          Leu Y
          Hsiao H
          Chang Y
          Yang C
          Lee J
          Chen Y
        affil: The Department of Otolaryngology-Head & Neck Surgery, Mackay Memorial Hospital, Taipei, Taiwan. lys@ms2.mmh.org.tw
      sug:
        subj:
          Deglutition Physiology
          Laryngeal Neoplasms Surgery
          Neoadjuvant Therapy
          Pharyngeal Neoplasms Surgery
          Speech Physiology
          Surgical Flaps
          Adult
          Antineoplastic Agents Therapeutic Use
          Carcinoma, Squamous Cell Radiotherapy
          Carcinoma, Squamous Cell Surgery
          Colon Transplantation
          Comparative Studies
          Descriptive Statistics
          Ileum Transplantation
          Laryngeal Neoplasms Radiotherapy
          Laryngectomy Rehabilitation
          Male
          Middle Age
          Neoplasm Recurrence, Local Pathology
          Pharyngeal Neoplasms Radiography
          Pharyngectomy Rehabilitation
          Prospective Studies
          Quality of Life
          Surgery, Reconstructive Methods
          Survival
          Treatment Outcomes
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
      ab: CONCLUSION: The new technique of ileocolic free flap reconstruction provides a better quality of life in terms of swallowing and speech for patients who have undergone laryngopharyngectomy with concomitant chemotherapy and radiotherapy (CCRT). OBJECTIVES: To compare and contrast the swallowing and speech outcomes of patients who underwent total laryngopharyngectomy with ileocolic free flap reconstruction and to analyze the survival rate after surgery and CCRT. MATERIAL AND METHODS: This was a follow-up study of 12 patients with advanced (stages III, IVA and IVB) laryngeal and hypopharyngeal cancer who underwent major surgery, CCRT (with one exception) and ileocolic free flap reconstruction. RESULTS: All patients were able to tolerate single-stage combined management comprising total laryngopharyngectomy with or without radical neck dissection plus ileocolic free flap reconstruction and postoperative CCRT (with one exception), without immediate morbidity or mortality. Eleven patients were diagnosed with hypopharyngeal cancer and one with laryngeal cancer. The mean interval between surgery and CCRT was 34.1 days. The mean follow-up period was 16.5 months. Four patients died during the follow-up period as a result of local recurrence (n=2), distant metastasis (n=1) and suicide (n=1). One patient was alive with disease despite neck recurrence.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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