Relationship of Helicobacter pylori specific IgG antibodies with serum magnesium in patients on maintenance hemodialysis.

Dyspeptic symptoms are quite common in patients on long-term hemodialysis, and Helicobacter pylori is thought to play an important role in the pathogenesis of active gastritis and other upper gastrointestinal mucosal lesions in these patients. This study investigated the probable association of seru...

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Publicado en:Journal of Applied Research Vol. 5; no. 3; pp. 438 - 444
Autores principales: Nasri H, Baradaran A
Formato: research tables/charts Journal Article
Publicado: Therapeutic Solutions LLC 2005
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2005
      vid: 5
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      pub: Therapeutic Solutions LLC
      place: Newtown, Pennsylvania
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        atl: Relationship of Helicobacter pylori specific IgG antibodies with serum magnesium in patients on maintenance hemodialysis.
      aug:
        au:
          Nasri H
          Baradaran A
        affil: Shahrekord University of Medical Sciences, Hajar Medical, Educational and Therapeutic Center (Section of Hemodialysis), Shahrekord, Iran
      sug:
        subj:
          Antibodies Blood
          Helicobacter Infections Complications
          Helicobacter Pylori
          Hemodialysis
          Magnesium Blood
          Adult
          Cross Sectional Studies
          Data Analysis Software
          Descriptive Statistics
          Female
          Gastrointestinal Diseases Symptoms
          Helicobacter Infections Physiopathology
          Immunoassay Methods
          Male
          Middle Age
          T-Tests
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Dyspeptic symptoms are quite common in patients on long-term hemodialysis, and Helicobacter pylori is thought to play an important role in the pathogenesis of active gastritis and other upper gastrointestinal mucosal lesions in these patients. This study investigated the probable association of serum magnesium (Mg[2+]) with H pylori infection in patients on maintenance therapy.H pylori specific IgG antibody titers and Mg' levels were measured in 44 patients on hemodialysis (34 nondiabetic and 10 diabetic). A positive correlation was found between anti H pylori IgG antibody titers with Mg[2+] in all patients, as well as an association between Mg[2+] with infection of H pylori. This study found Mg[2+] acquisition by CorA is essential for H pylori in vitro and that high Mg[2+] levels, and probably its higher concentration in gastric mucosa, might facilitate the colonization of H pylori in the stomachs of patients on hemodialysis. Further investigation is needed to define the clinical significance of this finding.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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