Comparison of urine urea nitrogen collection times in critically ill patients.

Twenty-four-hour urine urea nitrogen (UUN) collections are used to assess nitrogen loss in critically ill patients but are often difficult to obtain accurately. This prospective study compared 6- and 12-hour UUN collections with 24-hour UUN collections in critically ill patients receiving continuous...

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Publicado en:Nutrition in Clinical Practice Vol. 20; no. 2; pp. 271 - 276
Autores principales: Graves C, Saffle J, Morris S
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 2005 Apr
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2005 Apr
      vid: 20
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        2009127930
        10.1177/0115426505020002271
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        106328862
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        atl: Comparison of urine urea nitrogen collection times in critically ill patients.
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        au:
          Graves C
          Saffle J
          Morris S
        affil: Nutrition Care Service, University of Utah Hospital, 50 N Medical Dr, Salt Lake City, UT 84132; caran.graves@hsc.utah.edu
      sug:
        subj:
          Critical Illness
          Nutritional Support
          Nutritional Assessment Methods
          Nitrogen Metabolism
          Urea Urine
          Nitrogen Urine
          Time Factors
          Specimen Handling
          Comparative Studies
          Intensive Care Units
          Diagnosis, Laboratory
          Male
          Female
          Adolescence
          Adult
          Middle Age
          Aged
          Descriptive Statistics
          Critically Ill Patients
          Data Analysis Software
          Paired T-Tests
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Twenty-four-hour urine urea nitrogen (UUN) collections are used to assess nitrogen loss in critically ill patients but are often difficult to obtain accurately. This prospective study compared 6- and 12-hour UUN collections with 24-hour UUN collections in critically ill patients receiving continuous nutrition support. ICU patients admitted from September 1999 through January 2003 who had UUN collections as part of routine care were recruited into the study. Patients were not receiving oral diets, were receiving continuous parenteral or enteral nutrition, and had indwelling urinary catheters. We excluded patients with hepatic or renal failure. Urine samples were collected every 6 hours starting at 6:00 AM and kept refrigerated until the 24-hour collection was complete. Samples were analyzed using an automated urease enzymatic reaction. Samples were multiplied by a factor of 4 (6-hour samples) or 2 (12-hour samples) to estimate 24-hour totals and then compared with actual 24-hour totals. Twenty-four patients (18 men) completed the study; 21 patients had 6-hour samples (84 samples), and 24 patients had 12-hour samples (24 samples). Estimated 24-hour UUN from 6-hour (14.7-15.7 g/d) and 12-hour (15.2 g/d) samples did not differ significantly (p > .5) from actual 24-hour totals (15.1 g/d). Shortened UUN collection times may be used to estimate 24-hour nitrogen losses in critically ill patients receiving continuous nutrition support.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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