An automated screening assay for determination of aqueous equilibrium solubility enabling SPR study during drug lead optimization.
Aqueous solubility is one of the most critical physicochemical properties to be determined in the process of drug lead optimization. Particularly, an equilibrium solubility method is highly valuable to the study of structure property relationship (SPR), while meeting the needs of analytical sensitiv...
| Published in: | JALA: Journal of the Association for Laboratory Automation Vol. 10; no. 6; pp. 364 - 374 |
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| Main Authors: | , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Elsevier B.V.
Dec2005
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| Online Access: | View this record in EBSCOhost |