Optimal combination of discriminators for differentiating ventricular from supraventricular tachycardia by dual-chamber defibrillators.

Discriminators for ventricular/supraventricular tachycardia. INTRODUCTION: Dual-chamber implantable cardioverter defibrillators (ICDs) use discriminators to differentiate between supraventricular tachycardias (SVTs) and ventricular tachycardias (VT), the accuracy of which may depend on the type and...

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Published in:Journal of Cardiovascular Electrophysiology Vol. 16; no. 7; pp. 732 - 740
Main Authors: Glikson M, Swerdlow CD, Gurevitz OT, Daoud E, Shivkumar K, Wilkoff B, Shipman T, Friedman PA
Format: algorithm research tables/charts tracings Journal Article
Published: Wiley-Blackwell Jul2005
Online Access:View this record in EBSCOhost
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Optimal combination of discriminators for differentiating ventricular from supraventricular tachycardia by dual-chamber defibrillators.
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          Glikson M
          Swerdlow CD
          Gurevitz OT
          Daoud E
          Shivkumar K
          Wilkoff B
          Shipman T
          Friedman PA
        affil: Heart Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 52621, Israel; mglikson@post.tau.ac.il
      sug:
        subj:
          Defibrillators, Implantable
          Tachycardia, Supraventricular Diagnosis
          Tachycardia, Ventricular Diagnosis
          Adult
          Aged
          Aged, 80 and Over
          Data Analysis, Statistical
          Descriptive Statistics
          Female
          Israel
          Male
          Middle Age
          Prospective Studies
          Sensitivity and Specificity
          Tachycardia, Supraventricular Therapy
          Tachycardia, Ventricular Therapy
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Discriminators for ventricular/supraventricular tachycardia. INTRODUCTION: Dual-chamber implantable cardioverter defibrillators (ICDs) use discriminators to differentiate between supraventricular tachycardias (SVTs) and ventricular tachycardias (VT), the accuracy of which may depend on the type and method used. ICDs can combine rate branching of tachyarrhythmias according to their A:V relationship with two SVT-VT discriminators in each rate branch, using ANY (either) or ALL (both) logic. Our goal was to determine the optimal discriminator combination. METHODS: Stored electrogram data from 596 spontaneous tachyarrhythmias from 203 patients with Photon DR ICDs were analyzed. Arrhythmias are first classified by the relationship of atrial and ventricular rates (rate branches V<A, V=A, and V>A) followed by additional discriminators: morphology and/or sudden onset if V=A; morphology and/or interval stability if V<A. Data were analyzed for all combinations of ANY and ALL logic. RESULTS: Sensitivity and specificity were calculated for all spontaneous episodes in each analysis. V=A branch: ALL logic produced unacceptably low sensitivity, whereas morphology provided only similar sensitivity but better specificity than ANY logic. A>V branch: ANY logic provided adequate sensitivity. The combination of morphology only in V=A with interval stability or morphology (ANY logic) in V<A, provided the optimal result with sensitivity, specificity, positive, and negative predictive values of 99%, 79%, 87%, and 98%, respectively. CONCLUSION: SVT-VT combined discriminators strongly influence dual-chamber SVT-VT discrimination performance. In our study, optimal programming is morphology only in the V=A branch and morphology or interval stability (ANY) in the V<A branch. ALL logic should be used with caution due to loss of sensitivity.
      pubtype: Academic Journal
      doctype:
        algorithm
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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