Quantification of fatty tissue mass by magnetic resonance imaging in arrhythmogenic right ventricular dysplasia.

INTRODUCTION: Arrhythmogenic right ventricular dysplasia (ARVD) is a heart muscle disorder in which the pathological substrate is a fatty or fibro-fatty replacement of the right ventricular (RV) myocardium. METHODS AND RESULTS: Magnetic resonance imaging (MRI) studies were performed in 10 patients w...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Cardiovascular Electrophysiology Vol. 16; no. 3; pp. 256 - 262
Autores principales: Fattori R, Tricoci P, Russo V, Lovato L, Bacchi-Reggiani L, Gavelli G, Branzi A, Boriani G
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Mar2005
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106379070&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 106379070
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        10453873
        GSB
      jtl: Journal of Cardiovascular Electrophysiology
      issn: 10453873
      maglogo: Y
    pubinfo:
      dt: Mar2005
      vid: 16
      iid: 3
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
    artinfo:
      ui:
        106379070
        2009076357
        10.1046/j.1540-8167.2004.40498.x
        NLM15817082
        106379070
      ppf: 256
      ppct: 6
      formats:
        fmt:
          @attributes:
            type: P
      tig:
        atl: Quantification of fatty tissue mass by magnetic resonance imaging in arrhythmogenic right ventricular dysplasia.
      aug:
        au:
          Fattori R
          Tricoci P
          Russo V
          Lovato L
          Bacchi-Reggiani L
          Gavelli G
          Branzi A
          Boriani G
        affil: Department of Radiology, University Hospital S. Orsola-Malpighi, Bologna, Italy; ross@med.unibo.it
      sug:
        subj:
          Adipose Tissue
          Arrhythmia Physiopathology
          Heart Ventricle, Right Physiopathology
          Magnetic Resonance Imaging
          Adult
          Case Control Studies
          Data Analysis, Statistical
          Descriptive Statistics
          Female
          Italy
          Male
          Middle Age
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: INTRODUCTION: Arrhythmogenic right ventricular dysplasia (ARVD) is a heart muscle disorder in which the pathological substrate is a fatty or fibro-fatty replacement of the right ventricular (RV) myocardium. METHODS AND RESULTS: Magnetic resonance imaging (MRI) studies were performed in 10 patients with arrhythmogenic right ventricular dysplasia and in 24 matched controls in order to assess right ventricular epicardial/intramyocardial fatty tissue mass, RV myocardial mass, and RV functional parameters. Functional abnormalities were found in all ARVD cases. Patients with ARVD showed increased fatty tissue compared to controls (8.2 +/- 4 g vs. 2.0 +/- 1.0 g; P = 0.001), whereas no significant differences were found in RV myocardial mass (29.5 +/- 9.2 g vs. 23.2 +/- 6.7 g; P = NS). A correlation coefficient between 0.87 and 0.97 was found for repeated measurements. CONCLUSION: Quantification of fatty tissue with MRI is feasible and constitutes an objective method for differentiating normal from pathological conditions. This approach may lead to a complete diagnostic assessment of ARVD with the potential application for monitoring the evolution of the disease.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N