Fine needle aspiration cytology in the management of a parotid mass: a two centre retrospective study.

Objectives: There is a diversity of opinion regarding the role of fine needle aspiration cytology (FNAC) in the pre-operative evaluation of the parotid mass. This study further investigates the role of FNAC from the standpoint of the clinician attempting to resolve one or more clinical issues.Method...

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Publicado en:Surgeon (Edinburgh University Press) Vol. 3; no. 2; pp. 67 - 73
Autores principales: Balakrishnan K, Castling B, McMahon J, Imrie J, Feeley KM, Parker AJ, Bull PD, Johnston A, Balakrishnan, K, Castling, B, McMahon, J, Imrie, J, Feeley, K M, Parker, A J, Bull, P D, Johnston, A
Formato: exam questions research tables/charts Journal Article
Publicado: Edinburgh University Press Apr2005
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2005
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      pub: Edinburgh University Press
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        10.1016/s1479-666x(05)80064-2
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        atl: Fine needle aspiration cytology in the management of a parotid mass: a two centre retrospective study.
      aug:
        au:
          Balakrishnan K
          Castling B
          McMahon J
          Imrie J
          Feeley KM
          Parker AJ
          Bull PD
          Johnston A
          Balakrishnan, K
          Castling, B
          McMahon, J
          Imrie, J
          Feeley, K M
          Parker, A J
          Bull, P D
          Johnston, A
        affil: Monklands Hospital, Airdrie, Lanarkshire, UK
      sug:
        subj:
          Biopsy, Needle Evaluation
          Cytology
          Parotid Neoplasms Diagnosis
          Academic Medical Centers
          Confidence Intervals
          Histology
          Retrospective Design
          Sensitivity and Specificity
          United Kingdom
          Human
      ab: Objectives: There is a diversity of opinion regarding the role of fine needle aspiration cytology (FNAC) in the pre-operative evaluation of the parotid mass. This study further investigates the role of FNAC from the standpoint of the clinician attempting to resolve one or more clinical issues.Methods: A retrospective study conducted at two UK Hospitals with no overlap of cytopathologists or surgeons. Patients undergoing parotidectomy at each institution were identified from Pathology department databases. The definitive histopathological diagnosis was compared with any pre-operative FNAC diagnosis. Cytology results were classified as suggestive, non-diagnostic, sampling error, or misleading.Setting: The study was conducted in a District General Hospital and a University Teaching Hospital providing secondary care for each community.Results: For the University Teaching Hospital the sensitivity in distinguishing malignant from benign disease was 79% (95% CI 61-97%) with a specificity 84% (95% CI 73-95%). However, three of eight patients with a primary parotid salivary gland malignancy were reported as having benign disease on FNAC. For the participating District General Hospital the sensitivity in distinguishing malignant from benign disease was 38% (95% CI 13-63%) and specificity 95% (95% CI 73-95%).Conclusions: Fine needle aspiration cytology does not reliably distinguish a benign from a malignant primary salivary gland neoplasm in the participating institutions. Where clinical teams use FNAC in an attempt to resolve this clinical problem, the results should be interpreted with caution and an ongoing audit of performance is required.
      pubtype: Academic Journal
      doctype:
        exam questions
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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