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Current management of low-grade squamous intraepithelial lesion, high-grade squamous epithelial lesion, and atypical glandular cells.

The Bethesda System 2001 terminology has been widely adapted and should improve communication between pathologists and clinicians. Despite definitions for cytologic abnormalities, there will remain limitations in the ability of cytopathologists to uniformly classify Papanicolaou test abnormalities--...

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Published in:Clinical Obstetrics & Gynecology Vol. 48; no. 1; pp. 147 - 160
Main Authors: Soto-Wright V, Samuelson R, McLellan R
Format: tables/charts Journal Article
Published: Lippincott Williams & Wilkins Mar2005
Online Access:View this record in EBSCOhost
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: Current management of low-grade squamous intraepithelial lesion, high-grade squamous epithelial lesion, and atypical glandular cells.
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        au:
          Soto-Wright V
          Samuelson R
          McLellan R
        affil: Division of Gynecologic Oncology, Lahey Clinic Foundation, Inc, 41 Mall Road, Burlington, MA 01805; valena.soto.wright@lahey.org
      sug:
        subj:
          Carcinoma, Squamous Cell Diagnosis
          Cervix Neoplasms Diagnosis
          Carcinoma, Squamous Cell Classification
          Carcinoma, Squamous Cell Pathology
          Cervix Neoplasms Classification
          Cervix Neoplasms Pathology
          Female
          Female
      ab: The Bethesda System 2001 terminology has been widely adapted and should improve communication between pathologists and clinicians. Despite definitions for cytologic abnormalities, there will remain limitations in the ability of cytopathologists to uniformly classify Papanicolaou test abnormalities--particularly with ASC and AGC. Evidenced-based management guidelines from the ASCCP-sponsored consensus conference should provide more uniform, cost-effective strategies to evaluate women with abnormal Pap smears. Additionally, clinicians will need to examine and modify their traditional practice patterns to incorporate new knowledge regarding the natural history of cervical cancer precursors, including the association with high-risk HPV types. Adherence to the new evidence-based guidelines may optimize the triage and management of women with abnormal cervical cytology and lead to a future decline in the incidence of cervical cancer.
      pubtype: Academic Journal
      doctype:
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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