Prevalence of HIV, hepatitis C and syphilis among injecting drug users in Russia: a multi-city study.

Objectives To estimate the prevalence of HIV, hepatitis C virus (HCV) and syphilis in injecting drug users (IDUs) in Russia. Methods Unlinked anonymous cross-sectional survey of 1473 IDUs recruited from non-treatment settings in Moscow, Volgograd and Barnaul (Siberia), with oral fluid sample collect...

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Publicado en:Addiction Vol. 101; no. 2; pp. 252 - 267
Autores principales: Rhodes T, Platt L, Maximova S, Koshkina E, Latishevskaya N, Hickman M, Renton A, Bobrova N, McDonald T, Parry JV
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Feb2006
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
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        atl: Prevalence of HIV, hepatitis C and syphilis among injecting drug users in Russia: a multi-city study.
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        au:
          Rhodes T
          Platt L
          Maximova S
          Koshkina E
          Latishevskaya N
          Hickman M
          Renton A
          Bobrova N
          McDonald T
          Parry JV
        affil: Centre for Research on Drugs and Health Behaviour, The Reynolds Building, St. Dunstan's Road, Imperial College, London, London W6 8RP, UK; t.rhodes@imperial.ac.uk
      sug:
        subj:
          Hepatitis C Epidemiology
          HIV Infections Epidemiology
          Persons Who Use Intravenous Drugs
          Syphilis Epidemiology
          Adult
          Antibodies Analysis
          Conceptual Framework
          Confidence Intervals
          Correlation Coefficient
          Cross Sectional Studies
          Funding Source
          Hepatitis C Risk Factors
          HIV Infections Risk Factors
          Interviews
          Middle Age
          Multivariate Analysis
          Needle Sharing
          Odds Ratio
          Prevalence
          Prisoners
          Russia
          Saliva Analysis
          Self Report
          Univariate Statistics
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
      ab: Objectives To estimate the prevalence of HIV, hepatitis C virus (HCV) and syphilis in injecting drug users (IDUs) in Russia. Methods Unlinked anonymous cross-sectional survey of 1473 IDUs recruited from non-treatment settings in Moscow, Volgograd and Barnaul (Siberia), with oral fluid sample collection for HIV, HCV antibody (anti-HIV, anti-HCV) and syphilis testing. Results Prevalence of antibody to HIV was 14% in Moscow, 3% in Volgograd and 9% in Barnaul. HCV prevalence was 67% in Moscow, 70% in Volgograd and 54% in Barnaul. Prevalence of positive syphilis serology was 8% in Moscow, 20% in Volgograd and 6% in Barnaul. Half of those HIV positive and a third of those HCV positive were unaware of their positive status. Common risk factors associated with HIV and HCV infection across the cities included both direct and indirect sharing of injecting equipment and injection of home-produced drugs. Among environmental risk factors, we found increased odds of anti-HIV associated with being in prison in Moscow, and some association between official registration as a drug user and anti-HIV and anti-HCV. No associations were found between sexual risk behaviours and anti-HIV in any city. Conclusions HIV prevalence among IDUs was markedly higher than city routine surveillance data suggests and at potentially critical levels in terms of HIV prevention in two cities. HCV prevalence was high in all cities. Syphilis prevalence highlights the potential for sexual risk and sexual HIV transmission. Despite large-scale testing programmes, knowledge of positive status was poor. The scaling-up of harm reduction for IDUs in Russia, including sexual risk reduction, is an urgent priority.
      pubtype: Academic Journal
      doctype:
        research
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        Journal Article
      ougenre: Article
    language: English
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