Transient ischemic attack with infarction: a unique syndrome?
It is debated whether transient symptoms associated with infarction (TSI) are best considered a minor ischemic stroke, a subtype of transient ischemic attack (TIA), or a separate ischemic brain syndrome. We studied clinical and imaging features to establish similarities and differences among ischemi...
| Publicado en: | Annals of Neurology Vol. 57; no. 5; pp. 679 - 687 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
May2005
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106433373&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106433373 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03645134 1WM jtl: Annals of Neurology issn: 03645134 maglogo: Y pubinfo: dt: May2005 vid: 57 iid: 5 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 106433373 106433373 2009154075 NLM15852402 106433373 ppf: 679 ppct: 8 formats: tig: atl: Transient ischemic attack with infarction: a unique syndrome? aug: au: Ay H Koroshetz WJ Benner T Vangel MG Wu O Schwamm LH Sorensen AG affil: AA Martinos Center for Biomedical Imaging and Stroke Service, Department of Neurology and Radiology, Massachusetts General Hospital, CNY149-2301, Charlestown, MA 02129; hay@partners.org sug: subj: Cerebral Ischemia, Transient Physiopathology Acute Disease Aged Case Control Studies Cerebral Ischemia, Transient Risk Factors Comorbidity Data Analysis, Statistical Descriptive Statistics Female Funding Source Male Massachusetts Time Factors Human Aged: 65+ years Female Male ab: It is debated whether transient symptoms associated with infarction (TSI) are best considered a minor ischemic stroke, a subtype of transient ischemic attack (TIA), or a separate ischemic brain syndrome. We studied clinical and imaging features to establish similarities and differences among ischemic stroke, TIA without infarction, and TSI. Eighty-seven consecutive patients with TIA and 74 patients with ischemic stroke were studied. All underwent diffusion-weighted imaging on admission. Symptom duration and infarct volume were determined in each group. Thirty-six patients (41.3%) with TIA had acute infarct(s). Although TIA-related infarcts were smaller than those associated with ischemic stroke (mean, 0.7 vs 27.3 ml; p < 0.001), there was no lesion size threshold that distinguished ischemic stroke from TSI. In contrast, the symptom duration probability density curve was not broad, but instead peaked early with only a few patients having symptoms for longer than 200 minutes. The probability density function for symptom duration was similar between TIA with or without infarction. The in-hospital recurrent ischemic stroke and TIA rate was 19.4% in patients with TSI and 1.3% in those with ischemic stroke. TIA with infarction appears to have unique features separate from TIA without infarction and ischemic stroke. We propose identifying TSI as a separate clinical syndrome with distinct prognostic features. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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