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Effect of volume guarantee combined with assist/control vs synchronized intermittent mandatory ventilation.

OBJECTIVE: To compare the effect of combining assist/control with volume-guarantee (AC+VG) vs synchronized intermittent mandatory ventilation with VG (SIMV+VG) on tidal volume (V(T)), peak inspiratory pressure (PIP), mean airway pressure (MAP), respiratory rate, heart rate, oxygen saturation (SpO(2)...

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Publicado en:Journal of Perinatology Vol. 25; no. 10; pp. 638 - 643
Autores principales: Abubakar K, Keszler M
Formato: clinical trial research tables/charts Journal Article
Publicado: Springer Nature Oct2005
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2005
      vid: 25
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      pub: Springer Nature
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        10.1038/sj.jp.7211370
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        atl: Effect of volume guarantee combined with assist/control vs synchronized intermittent mandatory ventilation.
      aug:
        au:
          Abubakar K
          Keszler M
        affil: Division of Neonatology, M3400, Georgetown University Children's Medical Center, Washington, DC 20007
      sug:
        subj:
          Respiration, Artificial Methods
          Analysis of Variance
          Birth Weight
          Clinical Trials
          Comparative Studies
          Crossover Design
          Descriptive Statistics
          Gestational Age
          Heart Rate
          Infant, Newborn
          Infant, Premature
          Intensive Care Units, Neonatal
          Intensive Care, Neonatal
          Oxygen Saturation
          Pulse Oximetry
          Respiratory Rate
          T-Tests
          Tidal Volume Evaluation
          Treatment Outcomes
          Respiration, Artificial Evaluation
          Respiration, Artificial Utilization
          Ventilators, Mechanical
          Funding Source
          Human
          Infant, Newborn: birth-1 month
      ab: OBJECTIVE: To compare the effect of combining assist/control with volume-guarantee (AC+VG) vs synchronized intermittent mandatory ventilation with VG (SIMV+VG) on tidal volume (V(T)), peak inspiratory pressure (PIP), mean airway pressure (MAP), respiratory rate, heart rate, oxygen saturation (SpO(2)), and minute volume (MV) in preterm infants. STUDY DESIGN: A total of 12 infants were randomized to receive AC+VG, followed by SIMV+VG, or the opposite sequence for four alternating 2-hour periods. RESULTS: Airway pressure of machine breaths was higher during SIMV. MV and V(Te) were similar, but more variable during synchronized intermittent mandatory ventilation. The V(Te) of unsupported breaths during SIMV was lower than machine breaths of SIMV and AC. There was more tachycardia and tachypnea with a lower and more variable SpO(2) during SIMV. CONCLUSIONS: SIMV+VG is associated with higher work of breathing indicated by tachycardia, tachypnea and lower SpO(2) compared to AC+VG. VG appears to be more effective when combined with AC than with SIMV.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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