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Video analysis of sensory-motor features in infants with fragile X syndrome at 9-12 months of age.

This study utilized retrospective video analysis to distinguish sensory-motor patterns in infants with fragile X syndrome (FXS) (n = 11) from other infants [i.e., autism (n = 11), other developmental delay (n = 10), typical (n = 11)] at 9-12 months of age. Measures of development, autistic features,...

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Published in:Journal of Autism & Developmental Disorders Vol. 35; no. 5; pp. 645 - 657
Main Authors: Baranek GT, Danko CD, Skinner ML, Hatton DD, Roberts JE, Mirrett PL, Bailey DB Jr.
Format: research tables/charts Journal Article
Published: Springer Nature Oct2005
Online Access:View this record in EBSCOhost
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      dt: Oct2005
      vid: 35
      iid: 5
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      pub: Springer Nature
      place: New York, New York
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        106438454
        2009159106
        10.1007/s10803-005-0008-7
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        atl: Video analysis of sensory-motor features in infants with fragile X syndrome at 9-12 months of age.
      aug:
        au:
          Baranek GT
          Danko CD
          Skinner ML
          Hatton DD
          Roberts JE
          Mirrett PL
          Bailey DB Jr.
        affil: Division of Occupational Science, Department of Allied Health Sciences, University of North Carolina at Chapel Hill, CB#7120 UNC-CH Chapel Hill, NC 27599-7120
      sug:
        subj:
          Fragile X Syndrome
          Psychomotor Performance Evaluation
          Chi Square Test
          Descriptive Statistics
          Female
          Infant
          Interviews
          Intraclass Correlation Coefficient
          Male
          Multiple Logistic Regression
          One-Way Analysis of Variance
          P-Value
          Post Hoc Analysis
          Research Instruments
          Retrospective Design
          Scales
          Spearman's Rank Correlation Coefficient
          Videorecording
          Funding Source
          Human
          Infant: 1-23 months
          Female
          Male
      ab: This study utilized retrospective video analysis to distinguish sensory-motor patterns in infants with fragile X syndrome (FXS) (n = 11) from other infants [i.e., autism (n = 11), other developmental delay (n = 10), typical (n = 11)] at 9-12 months of age. Measures of development, autistic features, and FMRP were assessed at the time of entry into the study. Home videos collected from families were edited and coded with previously validated procedures. Findings revealed a pattern of sensory-motor features (e.g., repetitive leg movements, posturing, less sophistication/repetitive use of objects) associated with FXS, and suggest these infants were most similar to the group of infants with other developmental delays, irrespective of co-existing autistic symptoms later in life. Infant sensory-motor features in the FXS group were more predictive of an early developmental milestone (i.e., age walking) than later, more broad, developmental outcomes, or FMRP. Implications for early identification and differential diagnosis are discussed.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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