Tissue Doppler echocardiography reveals insufficient contractile reserve recruitment during effort in subjects with mitral valve prolapse and those with thick mitral valve.

OBJECTIVE: To assess by tissue Doppler echocardiography (TDE), the tissue velocities, both at rest and after exercise stress testing, in subjects with mitral valve prolapse (MVP) and those with thick mitral valve (TMV). METHODS: Twenty individuals with typical MVP, 30 with TMV, and 30 healthy contro...

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Publicado en:Echocardiography Vol. 23; no. 2; pp. 114 - 120
Autores principales: Zampoulakis JD, Karavidas AI, Matsakas E, Lazaros GA, Karaminas NT, Fotiadis IN, Panou FK, Zacharoulis A
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Feb2006
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2006
      vid: 23
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/j.1540-8175.2006.00184.x
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        atl: Tissue Doppler echocardiography reveals insufficient contractile reserve recruitment during effort in subjects with mitral valve prolapse and those with thick mitral valve.
      aug:
        au:
          Zampoulakis JD
          Karavidas AI
          Matsakas E
          Lazaros GA
          Karaminas NT
          Fotiadis IN
          Panou FK
          Zacharoulis A
        affil: Department of Cardiology, Athens General Hospital, Athens, Greece
      sug:
        subj:
          Echocardiography, Doppler
          Mitral Valve Insufficiency Ultrasonography
          Mitral Valve Prolapse Ultrasonography
          Adolescence
          Adult
          Age Factors
          Analysis of Variance
          Data Analysis Software
          Data Analysis, Statistical
          Descriptive Statistics
          Female
          Male
          Middle Age
          P-Value
          Spearman's Rank Correlation Coefficient
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: OBJECTIVE: To assess by tissue Doppler echocardiography (TDE), the tissue velocities, both at rest and after exercise stress testing, in subjects with mitral valve prolapse (MVP) and those with thick mitral valve (TMV). METHODS: Twenty individuals with typical MVP, 30 with TMV, and 30 healthy controls were enrolled. TDE was performed at the basal-inferior wall and the parameters evaluated were the S, Em, and Am velocities, as well as the Em/Am ratio. RESULTS: The mean S-wave at rest was higher in subjects with MVP compared to that of the TMV (P < 0.01) and the control groups (P = 0.00005), whereas after exercise it was higher in the control group compared to either MVP (P = 0.013) or TMV group (P = 0.00002). The mean Em wave at rest was higher in the control individuals both at rest (P = 0.007 compared with MVP group and P = 0.013 compared with TMV group), and after exercise (P = 0.0002 and 0.0009, respectively). The Am wave in the MVP group was higher compared with TMV and control subjects at rest (P = 0.022 and 0.00001, respectively) but it was not after exercise (P = ns for both comparisons). The Em/Am ratio of the control group at rest was higher than that of the MVP (P = 0.0000) and TMV (P = 0.00028) groups. However, after exercise, it was higher only when compared with the MVP group (P = 0.016). CONCLUSIONS: Subjects with MVP and those with TMV exhibit a less effective contractile response to exercise compared to healthy individuals. Some degree of diastolic dysfunction, particularly after exercise, was also detected in the individuals with MVP.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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