Control of scabies, skin sores and haematuria in children in the Solomon Islands: another role for ivermectin.
OBJECTIVE: To assess the effects of a 3-year programme aimed at controlling scabies on five small lagoon islands in the Solomon Islands by monitoring scabies, skin sores, streptococcal skin contamination, serology and haematuria in the island children. METHODS: Control was achieved by treating almos...
| Publicado en: | Bulletin of the World Health Organization Vol. 83; no. 1; pp. 34 - 43 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
World Health Organization
Jan2005
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106478695&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106478695 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00429686 BUW jtl: Bulletin of the World Health Organization issn: 00429686 maglogo: N pubinfo: dt: Jan2005 vid: 83 iid: 1 pid: 437 pub: World Health Organization artinfo: ui: 106478695 106478695 2005105058 NLM15682247 106478695 ppf: 34 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Control of scabies, skin sores and haematuria in children in the Solomon Islands: another role for ivermectin. aug: au: Lawrence G Leafasia J Sheridan J Hills S Wate J Wate C Montgomery J Pandeya N Purdie D affil: Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Post Office, Royal Brisbane Hospital, Queensland 4029, Australia; gregL@qimr.edu.au sug: subj: Disaccharides Therapeutic Use Hematuria Drug Therapy Scabies Drug Therapy Skin Ulcer Drug Therapy Funding Source Child Confidence Intervals Data Analysis Software Data Analysis, Statistical Descriptive Statistics Disaccharides Administration and Dosage Fisher's Exact Test Logistic Regression P-Value Human Solomon Islands Child: 6-12 years ab: OBJECTIVE: To assess the effects of a 3-year programme aimed at controlling scabies on five small lagoon islands in the Solomon Islands by monitoring scabies, skin sores, streptococcal skin contamination, serology and haematuria in the island children. METHODS: Control was achieved by treating almost all residents of each island once or twice within 2 weeks with ivermectin (160-250 microg/kg), except for children who weighed less than 15 kg and pregnant women, for whom 5% permethrin cream was used. Reintroduction of scabies was controlled by treating returning residents and visitors, whether or not they had evident scabies. FINDINGS: Prevalence of scabies dropped from 25% to less than 1% (P < 0.001); prevalence of sores from 40% to 21% (P < 0.001); streptococcal contamination of the fingers in those with and without sores decreased significantly (P = 0.02 and 0.047, respectively) and anti-DNase B levels decreased (P = 0.002). Both the proportion of children with haematuria and its mean level fell (P = 0.002 and P < 0.001, respectively). No adverse effects of the treatments were seen. CONCLUSION: The results show that ivermectin is an effective and practical agent in the control of scabies and that control reduces the occurrence of streptococcal skin disease and possible signs of renal damage in children. Integrating community-based control of scabies and streptococcal skin disease with planned programmes for controlling filariasis and intestinal nematodes could be both practical and produce great health benefits. Copyright © 2005 World Health Organization pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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