Folate and homocysteine levels in pregnancy...reprinted from British Journal of Biomedical Science 2004 61(2) with permission of the publisher
This study aims to determine serum folate and plasma homocysteine levels in healthy pregnant women following a live birth and compare them with healthy non-pregnant women. Fifty healthy gravid multiparous women are included in the study and 25 normal non-pregnant female subjects act as controls (gro...
| Publicado en: | Journal of Continuing Education Topics & Issues Vol. 7; no. 2; pp. 74 - 79 |
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| Autores principales: | , |
| Formato: | CEU exam questions research tables/charts Journal Article |
| Publicado: |
American Medical Technologists
Apr2005
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106490148&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106490148 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15228606 IKA jtl: Journal of Continuing Education Topics & Issues issn: 15228606 maglogo: N pubinfo: dt: Apr2005 vid: 7 iid: 2 pid: 13698 pub: American Medical Technologists place: Rosemont, Illinois artinfo: ui: 106490148 106490148 2005111690 106490148 ppf: 74 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Folate and homocysteine levels in pregnancy...reprinted from British Journal of Biomedical Science 2004 61(2) with permission of the publisher aug: au: Megahed MA Taher IM affil: Department of Biochemistry, Medical Research Institute, 165 El-Horreya Ave., Alexandria 21561, Egypt; mtcalex@link.net sug: subj: Folic Acid Blood Homocysteine Blood Descriptive Statistics Education, Continuing (Credit) Female Folic Acid Deficiency P-Value Pregnancy Prospective Studies T-Tests Human Female ab: This study aims to determine serum folate and plasma homocysteine levels in healthy pregnant women following a live birth and compare them with healthy non-pregnant women. Fifty healthy gravid multiparous women are included in the study and 25 normal non-pregnant female subjects act as controls (group I). The pregnant women are divided into two groups according to interpregnancy interval: group II (six months or less); group III (18-24 months). Venous blood samples are analyzed for red blood cell folate and homocysteine, vitamin B12 serum folate and albumin, and serum aminotransferases (ALT and AST). There was a significant decrease in red cell folate and serum folate in group II compared to the control group (P<0.001). Serum vitamin B12 showed no significant difference. Plasma homocysteine and serum albumin showed significant decreases in both groups II and III compared to the control group. (P<0.001) There was significant positive correlation between homocysteine and serum albumin in the three studied groups. (r=0.42, P<0.001; r=0.45, (P<0.001; r=0.51, (P<0.001, respectively). There was significant negative correlation between red cell folate and homocysteine in the three studied groups (r=0.48, P<0.001; r=-0.53, P<0.001; r=-0.49, P<0.001, respectively). Two cases in group H showed signs of intrauterine growth retardation. The results suggest that pregnant females with short inter-pregnancy intervals are more likely to develop folate deficiency. Educational strategies are required to increase folate awareness among women to promote the benefits of folic acid supplementation. Mandatory folate fortification of foods should be defined and monitored. pubtype: Academic Journal doctype: CEU exam questions research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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