Occurrence of Helicobacter pylori in dental plaque and saliva of dyspeptic patients.

BACKGROUND: Helicobacter pylori infection in the stomach is associated with gastric and duodenal ulcers, gastric cancers and gastric lymphoma. The organism is transmitted by ingestion, but the oral-oral route and the fecal-oral route are also suggested. The prevalence of infection with H. pylori in...

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Publicado en:Oral Diseases Vol. 11; no. 1; pp. 17 - 22
Autores principales: Kignel S, de Almeida Pina F, André EA, Mayer MPA, Birman EG
Formato: pictorial research Journal Article
Publicado: Wiley-Blackwell Jan2005
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2005
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      pub: Wiley-Blackwell
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        10.1111/j.1601-0825.2004.01043.x
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        atl: Occurrence of Helicobacter pylori in dental plaque and saliva of dyspeptic patients.
      aug:
        au:
          Kignel S
          de Almeida Pina F
          André EA
          Mayer MPA
          Birman EG
        affil: Department of Stomatology, School of Dentistry, Universidade de São Paulo, Brazil
      sug:
        subj:
          Dental Plaque Microbiology
          Dyspepsia Microbiology
          Helicobacter Pylori
          Saliva Microbiology
          Adolescence
          Adult
          Aged
          Brazil
          Child
          Descriptive Statistics
          DNA Analysis
          Epidemiological Research
          Female
          Male
          Microbiological Techniques
          Middle Age
          Polymerase Chain Reaction
          Sample Size
          Specimen Handling
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged: 65+ years
          Child: 6-12 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: BACKGROUND: Helicobacter pylori infection in the stomach is associated with gastric and duodenal ulcers, gastric cancers and gastric lymphoma. The organism is transmitted by ingestion, but the oral-oral route and the fecal-oral route are also suggested. The prevalence of infection with H. pylori in developing countries, including Brazil, is higher than in developed countries. PURPOSE: This study aimed to evaluate the role of the oral cavity as a reservoir of this species, by evaluating the occurrence of H. pylori in supragingival dental plaque and in saliva of Brazilian dyspeptic patients, whether harboring the organism or not in the stomach. MATERIAL AND METHODS: Forty-nine patients reporting dyspeptic symptoms were subjected to oral clinical examination and collection of saliva and supragingival dental plaque samples prior to the endoscopic examination. The detection of H. pylori in oral samples was performed by PCR using 16S rRNA primers. The bacteria were detected in stomach by means of the rapid urease test. RESULTS: Helicobacter pylori was detected in the stomach of 20 of 49 subjects reporting dyspeptic symptoms. The organism was detected in only one supragingival plaque sample, obtained from a patient positive for the urease test in the stomach and in none of the salivary samples. CONCLUSION: Supragingival dental plaque and saliva may not be relevant reservoirs of H. pylori.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        Journal Article
      ougenre: Article
    language: English
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