Continuous throughout rapid tissue processing revolutionizes histopathology workflow.

Continuous throughput rapid tissue processing (CT-RTP) has the potential to introduce dramatic changes into the practice of modern histopathology, a field which has been relatively unchanged for many years. These changes can be grouped into 3 major categories: 1) where we work, 2) how we work, and 3...

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Detalles Bibliográficos
Publicado en:Laboratory Medicine Vol. 36; no. 5; pp. 300 - 303
Autor principal: Vernon SE
Formato: pictorial tables/charts Journal Article
Publicado: Oxford University Press / USA May2005
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Continuous throughput rapid tissue processing (CT-RTP) has the potential to introduce dramatic changes into the practice of modern histopathology, a field which has been relatively unchanged for many years. These changes can be grouped into 3 major categories: 1) where we work, 2) how we work, and 3) when we work.The implementation of CT-RTP allows for rapid turn around of tissue biopsies, providing a standard hematoxylin and eosin stained slide, while preserving various macromolecules such as mRNA and proteins of interest for development of target directed therapies.Despite initial resistance to these changes, we have successfully implemented CT-RTP by recognizing the necessary changes in our work patterns, including location, re-education in gross tissue sectioning techniques, fixation, and schedule adjustments in both technical and professional staffing.