Randomised trial of parental support for families with very preterm children: outcome at 5 years.

Aims: To test the effectiveness of a home based developmental education intervention in improving outcome at 5 years for very preterm infants.Methods: The Avon Premature Infant Project (APIP) is a randomised controlled trial in which the parents of 284 babies born <33 weeks gestational age received...

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Publicado en:Archives of Disease in Childhood Vol. 90; no. 9; pp. 909 - 916
Autores principales: Johnson S, Ring W, Anderson P, Marlow N
Formato: clinical trial research tables/charts Journal Article
Publicado: BMJ Publishing Group Sep2005
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2005
      vid: 90
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      pub: BMJ Publishing Group
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        atl: Randomised trial of parental support for families with very preterm children: outcome at 5 years.
      aug:
        au:
          Johnson S
          Ring W
          Anderson P
          Marlow N
        affil: Division of Child Health, University of Nottingham, UK
      sug:
        subj:
          Developmental Disabilities Prevention and Control
          Early Childhood Intervention
          Infant, Premature
          Parents Education
          Support, Psychosocial
          Birth Weight
          Chi Square Test
          Child Behavior Checklist
          Child Development
          Clinical Trials
          Cognition
          Confidence Intervals
          Counseling
          Data Analysis Software
          Descriptive Statistics
          Female
          Funding Source
          Infant, Newborn
          Infant, Very Low Birth Weight
          Kruskal-Wallis Test
          Linear Regression
          Male
          Mann-Whitney U Test
          Motor Skills
          One-Way Analysis of Variance
          Random Assignment
          Relative Risk
          Scales
          Human
          Infant, Newborn: birth-1 month
          Female
          Male
      ab: Aims: To test the effectiveness of a home based developmental education intervention in improving outcome at 5 years for very preterm infants.Methods: The Avon Premature Infant Project (APIP) is a randomised controlled trial in which the parents of 284 babies born <33 weeks gestational age received a developmental education programme, a social support intervention, or standard care. A term reference population was also recruited. This study reports outcomes at 5 years (mean age 58 months 15 days) for 187 (66%) of these children without disability. Outcomes were assessed using the British Ability Scales II for cognitive development, the Movement ABC for motor impairment, and the Child Behavior Checklist for behavioural problems.Results: Preterm infants showed poorer cognitive performance than their term peers. Mean (SD) general conceptual ability (GCA) scores were: Portage 99.2 (15.7); parent adviser 100.3 (14.8); preterm control 101.1 (15.0); term reference 107.2 (13.4). There were no significant differences between preterm groups in GCA scores indicating no effect of either intervention. Similarly, there was no significant effect of intervention on behavioural or motor outcomes. Further analyses, in which outcome data were adjusted for social factors, did not reveal any differences between the three preterm groups or by subgroups classified by a range of perinatal variables.Conclusion: The small advantage shown at 2 years of age is no longer detectable at 5 years. These results question the effectiveness of early intervention in enhancing cognitive, behavioural, and motor function at 5 years.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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