Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial.

Background: Corticosteroids have been used to treat head injuries for more than 30 years. In 1997, findings of a systematic review suggested that these drugs reduce risk of death by 1-2%. The CRASH trial--a multicentre international collaboration--aimed to confirm or refute such an effect by recruit...

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Bibliographic Details
Published in:Lancet Vol. 364; no. 9442; pp. 1321 - 1329
Main Authors: Roberts, Ian, Yates, David, Sandercock, Peter, Farrell, Barbara, Wasserberg, Jonathan, Lomas, Gabrielle, Cottingham, Rowland, Svoboda, Petr, Brayley, Nigel, Mazairac, Guy, Laloë, Véronique, Muñoz-Sánchez, Angeles, Arango, Miguel, Hartzenberg, Bennie, Khamis, Hussein, Yutthakasemsunt, Surakrant, Komolafe, Edward, Olldashi, Fatos, Yadav, Yadram, Murillo-Cabezas, Francisco
Format: clinical trial research tables/charts Journal Article
Published: Lancet 10/9/2004
Online Access:View this record in EBSCOhost