Hormonal predictors of postnatal depression at 6 months in breastfeeding women.

Postnatal depression occurs in 10-15% of postpartum women. Studies have shown associations with endogenous hormone levels (oestrogen, progesterone, cortisol and thyroxin) and with autoimmune thyroid dysfunction. Breastfeeding has not been shown to increase the risk of developing postpartum depressio...

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Publicado en:Journal of Reproductive & Infant Psychology Vol. 21; no. 1; pp. 61 - 69
Autores principales: Ingram JC, Greenwood RJ, Woolridge MW
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Feb2003
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2003
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      pub: Taylor & Francis Ltd
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        atl: Hormonal predictors of postnatal depression at 6 months in breastfeeding women.
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        au:
          Ingram JC
          Greenwood RJ
          Woolridge MW
        affil: Institute of Child Health, University of Bristol, Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK
      sug:
        subj:
          Breast Feeding
          Depression, Postpartum Etiology
          Hormones Blood
          Mother-Infant Relations
          Mothers Psychosocial Factors
          Adult
          Body Mass Index
          Checklists
          Chi Square Test
          Data Analysis Software
          Depression, Postpartum Diagnosis
          Descriptive Statistics
          Edinburgh Postnatal Depression Scale
          Estradiol Blood
          Female
          Funding Source
          Interviews
          Linear Regression
          Multiple Logistic Regression
          Postnatal Period
          Pregnancy
          Progesterone Blood
          Prolactin Blood
          Prospective Studies
          Psychological Tests
          Questionnaires
          T-Tests
          Thyrotropin Blood
          United Kingdom
          Human
          Adult: 19-44 years
          Female
      ab: Postnatal depression occurs in 10-15% of postpartum women. Studies have shown associations with endogenous hormone levels (oestrogen, progesterone, cortisol and thyroxin) and with autoimmune thyroid dysfunction. Breastfeeding has not been shown to increase the risk of developing postpartum depression. A prospective study involving 54 breastfeeding mothers of mixed parity and similar socio-economic status and education used bivariate analysis to look for associations between hormone levels and postnatal depression. Total oestradiol, total progesterone, prolactin and thyrotropin (TSH) levels were determined at four time points (ante- and postnatally) from finger-prick blood spots by fluoro-immunoassay. EPDS and life event check lists were completed at 6 months postpartum. Ten women were screened positive for sub-clinical depression (score>/=10). Bivariate analysis showed that antenatal prolactin and postpartum progesterone levels were significantly associated with postnatal depression at 6 months (p=0.03). Only the result for progesterone persisted in a multiple logistic regression, which controlled for life events. Women with lower progesterone levels in the immediate postnatal period were more likely to be depressed at 6 months.
      pubtype: Academic Journal
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        Journal Article
      ougenre: Article
    language: English
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