Breast carcinogenesis -- can the examination of ductal fluid enhance our understanding?

PURPOSE/OBJECTIVES: To explore current breast carcinogenesis theories and the possibility of examining breast epithelial cells to confirm steps in the carcinogenic process and the relationship between intraductal sampling techniques and their role in enhanced risk prediction. DATA SOURCES: Published...

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Publicado en:Oncology Nursing Forum Vol. 32; no. 1; pp. 33 - 40
Autores principales: Baltzell K, Eder SE, Wrensch M
Formato: pictorial tables/charts Journal Article
Publicado: Oncology Nursing Society Jan2005
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2005
      vid: 32
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      pub: Oncology Nursing Society
      place: Pittsburgh, Pennsylvania
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        atl: Breast carcinogenesis -- can the examination of ductal fluid enhance our understanding?
      aug:
        au:
          Baltzell K
          Eder SE
          Wrensch M
      sug:
        subj:
          Breast Neoplasms Physiopathology
          Epithelial Cells Analysis
          Physiological Theory
          Biopsy, Needle
          Body Fluids Analysis
          Cytological Techniques
          Female
          Therapeutic Irrigation
          Models, Theoretical
          Nipples
          Oncogenes
          Risk Assessment
          Sensitivity and Specificity
          Female
      ab: PURPOSE/OBJECTIVES: To explore current breast carcinogenesis theories and the possibility of examining breast epithelial cells to confirm steps in the carcinogenic process and the relationship between intraductal sampling techniques and their role in enhanced risk prediction. DATA SOURCES: Published articles, textbooks, and conference proceedings. DATA SYNTHESIS: Examining breast epithelial cells may provide insight into the carcinogenic process while it is occurring. Methods of extracting breast epithelial cells include nipple aspiration, ductal lavage, and periareolar fine-needle aspiration. CONCLUSIONS: Nipple aspiration, ductal lavage, and periareolar fine-needle aspiration are viable means of examining possible precursors to breast tumors. Differentiating between true precursors and benign changes is an important step in breast cancer risk assessment. IMPLICATIONS FOR NURSING: Nipple aspiration and ductal lavage may be performed in an outpatient setting. RNs and advanced practice nurses may perform these procedures and discuss results with patients.
      pubtype: Academic Journal
      doctype:
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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