Lipemia: an overrated interference?...reprinted from the British Journal of Biomedical Science 2003 with permission of the publisher

Reagent method sheets for analysis of common serum analytes often highlight the possibility of interference from lipemia but the information given is often brief and may not be instrument-specific. This study assesses the degree of interference from lipemia in a range of common serum analytes on the...

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Publicado en:Journal of Continuing Education Topics & Issues Vol. 7; no. 1; pp. 44 - 48
Autores principales: Anderson NR, Slim S, Gama R, Holland MR
Formato: CEU exam questions research tables/charts Journal Article
Publicado: American Medical Technologists Jan2005
Acceso en línea:Ver este registro en EBSCOhost
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      pub: American Medical Technologists
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        atl: Lipemia: an overrated interference?...reprinted from the British Journal of Biomedical Science 2003 with permission of the publisher
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          Anderson NR
          Slim S
          Gama R
          Holland MR
        affil: Department of Clinical Chemistry, New Cross Hospital, Wolverhampton, U.K.
      sug:
        subj:
          Lipids Blood
          Descriptive Statistics
          Education, Continuing (Credit)
          Mann-Whitney U Test
          Paired T-Tests
          Wilcoxon Rank Sum Test
          Human
      ab: Reagent method sheets for analysis of common serum analytes often highlight the possibility of interference from lipemia but the information given is often brief and may not be instrument-specific. This study assesses the degree of interference from lipemia in a range of common serum analytes on the Bayer Opera (with a serum blank) using a commercial polymer, LipoClear, as a lipid-clearing agent. Serum samples (mean serum triglyceride 6.89 [range 0.58-28.4] mmol/L) are analyzed for 14 common chemistry analytes and the results compared be-fore and after treatment with LipoClear. Results showed no significant critical differences in analyte values before and after treatment, except for an expected fall in total protein, phosphate, cholesterol and triglyceride concentrations. Most of the common analytes in use on the Bayer Opera are not subject to interference from lipemia; how-ever, we recommend that where method sheets indicate interference from lipemia then this should be quantified for the analyte in question.
      pubtype: Academic Journal
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        CEU
        exam questions
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    language: English
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