Tumor necrosis factor alpha inhibitors for the treatment of dermatologic diseases.
Tumor necrosis factor alpha (TNFalpha) is involved in cell differentiation, mitogenesis, cytotoxic responses, inflammation, immunomodulation, and wound healing. Because of its numerous roles, it was thought that inhibition of TNF may aid in the treatment of certain dermatologic diseases such as psor...
| Publicado en: | Dermatology Nursing Vol. 17; no. 2; pp. 97 - 109 |
|---|---|
| Autores principales: | , |
| Formato: | CEU pictorial Journal Article |
| Publicado: |
Jannetti Publications, Inc.
Apr2005
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | Tumor necrosis factor alpha (TNFalpha) is involved in cell differentiation, mitogenesis, cytotoxic responses, inflammation, immunomodulation, and wound healing. Because of its numerous roles, it was thought that inhibition of TNF may aid in the treatment of certain dermatologic diseases such as psoriasis, hidradentitis suppurativa, pyoderma gangrenosum, Behcet's syndrome, and graft versus host disease. The efficacy of these agents has proven impressive and short-term side effects have been few and relatively benign. |
|---|