The rise of buprenorphine prescribing in England: analysis of NHS regional data, 2001-03.

AIMS: Since its launch in the prescribing market in 1999 for the treatment of opiate dependence, buprenorphine has rapidly become established as an alternative to methadone treatment in the United Kingdom. In the absence of evidence of its clinical superiority over methadone, and given its high rela...

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Publicado en:Addiction Vol. 100; no. 4; pp. 495 - 500
Autores principales: de Wet CJ, Reed LJ, Bearn J
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Apr2005
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
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        atl: The rise of buprenorphine prescribing in England: analysis of NHS regional data, 2001-03.
      aug:
        au:
          de Wet CJ
          Reed LJ
          Bearn J
        affil: Wickham Park House, South London and Maudsley NHS Trust, Bethlem Royal Hospital, Beckenham, Kent
      sug:
        subj:
          Buprenorphine Therapeutic Use
          Substance Dependence Drug Therapy
          Costs and Cost Analysis
          England
          Methadone Therapeutic Use
          National Health Programs
          Pharmacy, Retail
          Human
      ab: AIMS: Since its launch in the prescribing market in 1999 for the treatment of opiate dependence, buprenorphine has rapidly become established as an alternative to methadone treatment in the United Kingdom. In the absence of evidence of its clinical superiority over methadone, and given its high relative cost, we sought to examine the impact of buprenorphine availability on opiate treatment services in England. METHODS: Quarterly buprenorphine and methadone community prescription figures were obtained for 28 Strategic Health Authorities (SHAs) in England, for the 2-year period September 2001 to September 2003. Rates of buprenorphine prescribing (as proportion of all opiate prescriptions) were examined over time by number of prescriptions and net ingredient cost. RESULTS: Buprenorphine prescription rates increased disproportionately to methadone in all 28 SHAs. By the end of 2003 the number of buprenorphine prescriptions had increased to 23% of all opiate prescriptions, but accounted for 45% of opiate prescription costs in England. Buprenorphine prescribing rates varied substantially across different regions. CONCLUSIONS: Buprenorphine prescribing has increased dramatically and represents a disproportionately large fraction of community opiate prescribing costs. The marked regional variation suggests the need for further research and the development of national guidelines to support rational prescribing and equitable access to treatment.
      pubtype: Academic Journal
      doctype:
        research
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      ougenre: Article
    language: English
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