Characterization of apatite formed on alkaline-heat-treated Ti.

Alkaline-heat-treated titanium self-forms an apatite surface layer in vivo. The aim of the present study was to materialistically characterize the surface of alkaline-heat-treated titanium immersed in simulated body fluid (AHS-TI) and to examine the differentiation behavior of osteoblasts on AHS-TI....

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Publicado en:Journal of Dental Research Vol. 83; no. 6; pp. 465 - 470
Autores principales: Chosa N, Taira M, Saitoh S, Sato N, Araki Y, Chosa, N, Taira, M, Saitoh, S, Sato, N, Araki, Y
Formato: pictorial research tables/charts Journal Article
Publicado: Sage Publications Inc. Jun2004
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2004
      vid: 83
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Characterization of apatite formed on alkaline-heat-treated Ti.
      aug:
        au:
          Chosa N
          Taira M
          Saitoh S
          Sato N
          Araki Y
          Chosa, N
          Taira, M
          Saitoh, S
          Sato, N
          Araki, Y
        affil: Department of Biochemistry, Iwate Medical University School of Dentistry, Morioka, Iwate, Japan
      sug:
        subj:
          Connective Tissue Cells
          Titanium
          Microscopy, Electron, Scanning
          Spectroscopy, Near-Infrared
          T-Tests
          Funding Source
          Human
      ab: Alkaline-heat-treated titanium self-forms an apatite surface layer in vivo. The aim of the present study was to materialistically characterize the surface of alkaline-heat-treated titanium immersed in simulated body fluid (AHS-TI) and to examine the differentiation behavior of osteoblasts on AHS-TI. SEM, thin-film XRD, FTIR, and XPS analyses revealed that AHS-TI contained a 1.0- micro m-thick, low-crystalline, and [002] direction-oriented carbonate apatite surface. Human osteoblast-like SaOS-2 cells were cultured on polystyrene, titanium, and AHS-TI, and RT-PCR analyses of osteogenic differentiation-related mRNAs were conducted. On AHS-TI, the expression of bone sialoprotein mRNA was up-regulated as compared with that on polystyrene and titanium (p < 0.05). On AHS-TI, the expression of osteopontin and osteocalcin mRNAs was up-regulated as compared with that on polystyrene (p<0.05). The results indicate that the apatite was bone-like and accelerated the osteogenic differentiation of SaOS-2, suggesting that alkaline-heat treatment might facilitate better integration of titanium implants with bone.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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