Heart rate turbulence after ventricular and atrial premature beats in subjects without structural heart disease.

INTRODUCTION: Studies assessing heart rate (HR) behavior after premature beats have focused on HR responses to ventricular premature beats (VBPs), but there is less information of HR behavior after atrial premature beats (APBs). METHODS AND RESULTS: HR turbulence after VPBs and APBs was first measur...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 14; no. 5; pp. 447 - 453
Autores principales: Lindgren KS, Mäkikallio TH, Seppänen T, Raatikainen MJP, Castellanos A, Myerburg RJ, Huikuri HV
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell May2003
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2003
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      pub: Wiley-Blackwell
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        atl: Heart rate turbulence after ventricular and atrial premature beats in subjects without structural heart disease.
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        au:
          Lindgren KS
          Mäkikallio TH
          Seppänen T
          Raatikainen MJP
          Castellanos A
          Myerburg RJ
          Huikuri HV
        affil: Division of Cardiology, Department of Medicine, University of Oulu, Hospital, Oulu, Finland
      sug:
        subj:
          Heart Rate Physiology
          Premature Atrial Contractions Physiopathology
          Premature Ventricular Contractions Physiopathology
          Adult
          Descriptive Statistics
          Electrocardiography, Ambulatory
          Electrophysiology
          Female
          Funding Source
          Male
          Middle Age
          Pearson's Correlation Coefficient
          Spearman's Rank Correlation Coefficient
          T-Tests
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: INTRODUCTION: Studies assessing heart rate (HR) behavior after premature beats have focused on HR responses to ventricular premature beats (VBPs), but there is less information of HR behavior after atrial premature beats (APBs). METHODS AND RESULTS: HR turbulence after VPBs and APBs was first measured in response to ambient APBs and VPBs occurring during 24-hour ambulatory ECG recordings in 29 subjects without structural heart disease, and in response to programmed atrial (AE) and ventricular extrastimuli (VE) in 6 subjects undergoing electrophysiologic (EP) examination. Turbulence onset (TO) was more negative (-2.3 +/- 3.2% vs -0.9 +/- 2.8%, P < 0.01) and turbulence slope (TS) was steeper (11 +/- 11 vs 5.1 +/- 4.1 msec/R-R interval, P < 0.05) after VPBs than APBs. Compared to VPBs, the acceleration of HR after APBs was delayed by one beat, and APBs were associated with a short R-R interval preceding the APB, resulting in a blunted TO. Studies of patients undergoing an EP test confirmed the one-beat delay of HR acceleration and the blunted TO after programmed AE compared to VE (P < 0.05). TO and TS after VPBs were related to baroreflex sensitivity. TO also was related to 24-hour standard deviation of N-N intervals (SDNN). However, the TO or TS following APBs was not related to either SDNN or baroreflex sensitivity. CONCLUSION: HR behavior is different in response to APBs and VBPs among subjects without structural heart disease. Different definitions and calculation formulas should be used in the analysis of HR turbulence after APBs and VPBs.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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