Can nitroglycerine ointment facilitate newborn heelstick blood collection? A randomized controlled trial.

Newborn heelstick blood collection can be a painful procedure in part because of the time required to obtain sufficient quantity of blood. No previous studies have determined whether local vasodilatation using topical nitroglycerine ointment (NGO) would facilitate heelstick blood collection. OBJECTI...

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Publicado en:Journal of Perinatology Vol. 23; no. 4; pp. 304 - 307
Autores principales: Cecchi LM, Lerer T, Herson VC
Formato: research randomized controlled trial Journal Article
Publicado: Springer Nature Jun2003
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2003
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      pub: Springer Nature
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        atl: Can nitroglycerine ointment facilitate newborn heelstick blood collection? A randomized controlled trial.
      aug:
        au:
          Cecchi LM
          Lerer T
          Herson VC
        affil: Trinity College, Connecticut Children's Medical Center, Hartford, CT
      sug:
        subj:
          Treatment Related Pain Prevention and Control
          Blood Specimen Collection Methods
          Administration, Topical
          Blood Pressure Drug Effects
          Blood Specimen Collection Adverse Effects
          Ointments
          Heel
          Crying
          Infant Behavior
          Heart Rate Drug Effects
          Clinical Trials
          Placebos
          Infant, Newborn
          Human
          Infant, Newborn: birth-1 month
      ab: Newborn heelstick blood collection can be a painful procedure in part because of the time required to obtain sufficient quantity of blood. No previous studies have determined whether local vasodilatation using topical nitroglycerine ointment (NGO) would facilitate heelstick blood collection. OBJECTIVE: To determine if the topical application of NGO would reduce the time needed to collect the required amount of blood for newborn metabolic screening and, in turn, reduce the pain/distress of the procedure. STUDY DESIGN: In a randomized, prospective, placebo controlled and blinded fashion, term newborns in a well nursery received either topical nitroglycerine or placebo ointment 10 minutes prior to heelstick. Total time and number of heelsticks required to complete the collection were measured along with crying time, heart rate and blood pressure. RESULTS: In all, 50 were studied, 25 in each group. There was no statistical difference between groups in collection time, crying time or number of heelsticks required for completion. Heart rate increased significantly and equally in both groups. Blood pressures were unchanged. CONCLUSIONS: Topical NGO did not facilitate heelstick blood collection or reduce the pain/distress of the procedure.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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