Long-term developmental outcomes of children identified through a newborn screening program with a metabolic or endocrine disorder: a population-based approach.
Objective: To conduct surveillance of the developmental status of children who screen positive and are diagnosed with a metabolic or endocrine disorder.Study Design: The Centers for Disease Control and Prevention linked three data sources in Georgia: (1) Metropolitan Atlanta Developmental Disabiliti...
| Published in: | Journal of Pediatrics Vol. 143; no. 2; pp. 236 - 243 |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Elsevier B.V.
2003 Aug
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106729007&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106729007 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00223476 04M jtl: Journal of Pediatrics issn: 00223476 maglogo: N pubinfo: dt: 2003 Aug vid: 143 iid: 2 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 106729007 106729007 NLM12970640 2004062006 10.1067/s0022-3476(03)00358-5 NLM12970640 106729007 ppf: 236 ppct: 7 formats: tig: atl: Long-term developmental outcomes of children identified through a newborn screening program with a metabolic or endocrine disorder: a population-based approach. aug: au: Braun KVN Yeargin-Allsopp M Schendel D Fernhoff P Van Naarden Braun, Kim Yeargin-Allsopp, Marshalyn Schendel, Diana Fernhoff, Paul affil: Developmental Disabilities Team, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-86, Atlanta, GA 30333, USA sug: subj: Developmental Disabilities Complications Endocrine Diseases Complications Metabolism, Inborn Errors Complications Child Child, Preschool Databases, Health Disease Surveillance Epidemiological Research Georgia Intellectual Disability Neonatal Assessment Record Review Retrospective Design Human Child: 6-12 years Child, Preschool: 2-5 years ab: Objective: To conduct surveillance of the developmental status of children who screen positive and are diagnosed with a metabolic or endocrine disorder.Study Design: The Centers for Disease Control and Prevention linked three data sources in Georgia: (1) Metropolitan Atlanta Developmental Disabilities Surveillance Program (MADDSP), (2) Special Education Database of Metropolitan Atlanta (SEDMA), and (3) State of Georgia Newborn Blood-Spot Screening Program (NBSP).Results: When MADDSP and NBSP were linked (birth cohorts 1981-1991), of an estimated 147 infants who screened positive for a metabolic or endocrine disorder and were at risk for mental retardation if left untreated, only three children were identified with mental retardation. When SEDMA and NBSP were linked (birth cohorts 1981-1995), of an estimated 216 children who screened positive for a metabolic or endocrine disorder, nine children were identified as having a developmental disability less severe than mental retardation, eg, speech and language impairments.Conclusions: Although children found in MADDSP or SEDMA have a low occurrence of developmental disabilities attributable to these metabolic or endocrine disorders, our finding of cases of developmental disabilities of varying severity attributable to a metabolic or endocrine disorder suggests a need for ongoing population-based monitoring of the long-term developmental outcomes of children identified through newborn screening programs. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|