Tandem mass spectrometry in newborn screening: a primer for neonatal and perinatal nurses.
Since 1961, newborn screening for errors of metabolism (EM) has improved the diagnosis, treatment and outcome of newborns with an EM. Recently, advances in laboratory technology with tandem mass spectrometry (MS/MS) has increased the identification of newborns with an EM. With a single dried filter...
| Publicado en: | Journal of Perinatal & Neonatal Nursing Vol. 18; no. 1; pp. 41 - 61 |
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| Autores principales: | , |
| Formato: | CEU exam questions pictorial review tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Jan-Mar2004
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106734088&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106734088 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08932190 0O1 jtl: Journal of Perinatal & Neonatal Nursing issn: 08932190 maglogo: N pubinfo: dt: Jan-Mar2004 vid: 18 iid: 1 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 106734088 106734088 2004074268 10.1097/00005237-200401000-00005 NLM15027667 106734088 ppf: 41 ppct: 20 formats: fmt: @attributes: type: P tig: atl: Tandem mass spectrometry in newborn screening: a primer for neonatal and perinatal nurses. aug: au: Banta-Wright SA Steiner RD affil: Division of Metabolism, Department of Pediatrics, Child Development & Rehabilitation Center, Oregon Health & Science University, 707 SW Gaines Rd, Portland, OR 97239; bantawrs@ohsu.edu sug: subj: Health Screening In Infancy and Childhood Metabolism, Inborn Errors Diagnosis Neonatal Assessment Mass Spectrometry In Infancy and Childhood Acid-Base Imbalance Amino Acid Metabolism, Inborn Errors Diagnosis Amino Acids Carnitine Education, Continuing (Credit) Enzymes False Negative Results False Positive Results Fatty Acids Infant, Newborn Metabolism, Inborn Errors Classification Phenylketonuria Phenylketonuria Physiopathology Mass Spectrometry Equipment and Supplies Infant, Newborn: birth-1 month ab: Since 1961, newborn screening for errors of metabolism (EM) has improved the diagnosis, treatment and outcome of newborns with an EM. Recently, advances in laboratory technology with tandem mass spectrometry (MS/MS) has increased the identification of newborns with an EM. With a single dried filter paper blood spot (Guthrie R, Susi A. A simple phenylalanine method for detecting PKU in large populations of newborn infants. Pediatrics. 1963;32:338-343), MS/MS can identify more than 30 disorders of metabolism. This review will explore MS/MS to provide a better understanding of the development and application of this technology to newborn screening for perinatal and neonatal nurses. pubtype: Academic Journal doctype: CEU exam questions pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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