Optimizing testing and treatment of Helicobacter pylori infection in patients with acutely bleeding gastroduodenal ulcers: an interventional study.
Objective: To determine whether dissemination of inpatient practice guidelines for Helicobacter pylori management improves the testing and treatment rates of patients admitted with acute upper gastrointestinal (GI) bleeding from gastric or duodenal ulcers. Design: Prospective, non-randomized, interv...
| Publicado en: | Journal of Clinical Outcomes Management Vol. 10; no. 7; pp. 365 - 371 |
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| Autores principales: | , , , , , |
| Formato: | clinical trial research tables/charts Journal Article |
| Publicado: |
Frontline Medical Communications
2003 Jul
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106742281&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106742281 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10796533 Z0E jtl: Journal of Clinical Outcomes Management issn: 10796533 maglogo: N pubinfo: dt: 2003 Jul vid: 10 iid: 7 pid: 11942 pub: Frontline Medical Communications place: Newark, New Jersey artinfo: ui: 106742281 106742281 2004091822 106742281 ppf: 365 ppct: 6 formats: tig: atl: Optimizing testing and treatment of Helicobacter pylori infection in patients with acutely bleeding gastroduodenal ulcers: an interventional study. aug: au: Wong RCK Catanzaro A Gonet JA Chak A Sivak MV Jr. Cooper GS affil: Division of Gastroenterology (Wearn 247), University Hospitals of Cleveland, 11100 Euclid Ave, Cleveland, OH 44106-5066 sug: subj: Helicobacter Infections Diagnosis Helicobacter Infections Drug Therapy Peptic Ulcer Diagnosis Peptic Ulcer Drug Therapy Chi Square Test Clinical Trials Data Analysis Software Data Analysis, Statistical Descriptive Statistics Helicobacter Pylori Medication Compliance P-Value Human ab: Objective: To determine whether dissemination of inpatient practice guidelines for Helicobacter pylori management improves the testing and treatment rates of patients admitted with acute upper gastrointestinal (GI) bleeding from gastric or duodenal ulcers. Design: Prospective, non-randomized, interventional study. Setting and patients: 189 patients admitted to a single, urban academic medical center with a primary diagnosis of acute upper GI bleeding from gastric or duodenal ulcers between January 1998 and June 1999. The patients were managed by 18 gastroenterology physicians (12 staff, 6 private practice). Outcome measures: Rate and type of testing used for the diagnosis of H. pylori infection and the rate of initiation of appropriate anti-H. pylori therapy. Interventions: Outcomes were measured during a 6-month baseline period before dissemination of guidelines to gastroenterologists and during a 1-year period after dissemination of guidelines. In the year following dissemination, chart reminders and contacts by a physician opinion leader were used to increase physicians' adherence to the guidelines. Results: Testing for H. pylori increased from 78% in the baseline group (n = 58) to 88% in the postintervention group (n = 131) (P= 0.081). Testing for H. pylori using the rapid urease method increased from 27% in the baseline group to 51% in the postintervention group (P = 0.004). There was a highly significant increase in the rate of initiation of appropriate anti-H. pylori therapy (before hospital discharge) from 45% in the baseline group to 84% in the postintervention group (P < 0.001). Conclusion: H. pylori treatment can be markedly improved in patients admitted with acutely bleeding gastroduodenal ulcers by the active promotion of inpatient care guidelines. pubtype: Academic Journal doctype: clinical trial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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