Abstinence rates and predictors of outcome for smoking cessation: do Brazilian smokers need special strategies?
AIMS: To study tobacco abstinence and risk factors for failure in smoking cessation program and to evaluate the need for special strategies in a Brazilian cohort of smokers. DESIGN: A non-randomized, prospective, open clinical trial. PATIENTS AND METHODS: We studied smokers who attended the Smoking...
| Publicado en: | Addiction Vol. 99; no. 6; pp. 778 - 785 |
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| Autores principales: | , , , , |
| Formato: | clinical trial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jun2004
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106761672&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106761672 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09652140 AIO jtl: Addiction issn: 09652140 maglogo: Y pubinfo: dt: Jun2004 vid: 99 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 106761672 106761672 2004130136 10.1111/j.1360-0443.2004.00755.x NLM15139876 106761672 ppf: 778 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Abstinence rates and predictors of outcome for smoking cessation: do Brazilian smokers need special strategies? aug: au: Chatkin JM de Abreu CM Haggstram FM Wagner MB Fritscher CC sug: subj: Smoking Cessation Treatment Outcomes Adolescence Adult Aged Behavior Therapy Brazil Bupropion Therapeutic Use Clinical Trials Confidence Intervals Cox Proportional Hazards Model Data Analysis Software Female Kaplan-Meier Estimator Male Middle Age Nicotine Replacement Therapy Prospective Studies Questionnaires Human Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: AIMS: To study tobacco abstinence and risk factors for failure in smoking cessation program and to evaluate the need for special strategies in a Brazilian cohort of smokers. DESIGN: A non-randomized, prospective, open clinical trial. PATIENTS AND METHODS: We studied smokers who attended the Smoking Cessation Clinics of Hospital Sao Lucas da PUCRS, in Porto Alegre, Brazil between July, 1999 and June, 2003. All participated in the same behavioral therapy program and, according to the Fagerstrom test, also received nicotine patches and/or bupropion. Sustained abstinence was confirmed by exhaled CO measurements </= 10 parts per million (p.p.m.). Quit rates were evaluated at 12 months. The study included 381 patients (62% women, mean age +/- SD 47.4 +/- 11.5 years). FINDINGS: Smokers treated with only counseling, counseling + NRT, counseling + bupropion, and counseling + bupropion + NRT had an abstinence rates at the end of 12 months of 14.5%, 25.4%, 22.8% and 38.5%, respectively (P < 0.001). The estimated success rate was 23.2% at 12 months. The likelihood of failure in smoking cessation at the end of 12 months increased with higher nicotine dependence (HR: 1.63; 95% CI: 1.13-2.35; P = 0.009). Failure occurred significantly less in those patients treated with counseling + NRT + bupropion (HR: 0.39; 95% CI: 0.24-0.63 P < 0.001). CONCLUSIONS: The higher percentage of smoking cessation was achieved using multiple therapies (counseling + NRT + bupropion). The only significant predictor of failure detected was severe nicotine dependence. pubtype: Academic Journal doctype: clinical trial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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