BRCA1: mechanisms of inactivation and implications for management of patients.
The BRCA1 gene was cloned in 1994 as one of the genes that conferred genetic predisposition to early-onset breast and ovarian cancer. Since then, a genetic test for identification of high-risk individuals has been developed. Despite being implicated in many important cellular pathways, including DNA...
| Publicado en: | Lancet Vol. 360; no. 9338; pp. 1007 - 1015 |
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| Autores principales: | , , , , , , , |
| Formato: | review tables/charts Journal Article |
| Publicado: |
Lancet
9/28/2002
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| Acceso en línea: | Ver este registro en EBSCOhost |