Clinical validation of methods of diagnosis of neuropathy in a field study of United Kingdom sheep dippers.
Objectives: To investigate the reproducibility of measured indices of chronic peripheral neuropathy from a field study of sheep dippers when compared with similar measurements carried out in a clinical setting.Methods: A stratified random sample of field study subjects was invited to attend a clinic...
| Publicado en: | Occupational & Environmental Medicine Vol. 59; no. 7; pp. 442 - 447 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
BMJ Publishing Group
Jul2002
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106804560&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106804560 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13510711 22H jtl: Occupational & Environmental Medicine issn: 13510711 maglogo: N pubinfo: dt: Jul2002 vid: 59 iid: 7 pid: 8280 pub: BMJ Publishing Group artinfo: ui: 106804560 106804560 NLM12107291 2003031761 10.1136/oem.59.7.442 NLM12107291 106804560 ppf: 442 ppct: 5 formats: tig: atl: Clinical validation of methods of diagnosis of neuropathy in a field study of United Kingdom sheep dippers. aug: au: Buchanan D Jamal GA Pilkington A Hansen S Buchanan, D Jamal, G A Pilkington, A Hansen, S affil: ISD, Scottish Executive, Edinburgh, UK Wellwork Ltd, Edinburgh, UK Department of Neurology, Charing Cross Hospital, London, UK Department of Neurology, INS, Southern General Hospital, Glasgow, UK sug: subj: Farmworkers Peripheral Nervous System Diseases Diagnosis Insecticides Adverse Effects Male Female Adult Middle Age Aged Chronic Disease Sensation Disorders Diagnosis Sheep Reproducibility of Results Chi Square Test kappa Statistic Data Analysis Software Descriptive Statistics Scales Questionnaires Statistical Significance Odds Ratio Funding Source Human Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objectives: To investigate the reproducibility of measured indices of chronic peripheral neuropathy from a field study of sheep dippers when compared with similar measurements carried out in a clinical setting.Methods: A stratified random sample of field study subjects was invited to attend a clinic. Neuropathy was measured both in the field and at the clinic with a modified version of a standard symptoms questionnaire and quantitative sensory thresholds for hot, cold, and vibration. These were combined into a classification of the likelihood of neuropathy with a neuropathy scoring system. Indicators of sensory abnormality were based on comparison of sensory thresholds to age dependent reference values derived from an external reference group.Results: Only 51% of subjects were assigned similar classifications in the field and clinic based on the neuropathy scoring system. Of the component indices, grouped symptom scores, with 65% of subjects showing exact agreement, proved to be more reproducible than quantitative sensory test indicators. There were biases in the comparison of field and clinic measurements of hot and vibration sensations, but no evidence of greater variation between individual people in sensory thresholds in the field relative to at the clinic.Conclusions: The neuropathy scoring system proved to be of limited reproducibility, due in a large part to the lack of reproducibility of the indicators of sensory test abnormality caused by inadequate temperature control. However, the symptoms score and measured sensory thresholds could be used separately as indices of neuropathy in exposure-response analyses. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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