Treatment of acute otitis media in patients with a reported penicillin allergy.

Otitis media occurs commonly in children, and is usually treated with an antibiotic. In this case report, amoxicillin was prescribed for a 6-year-old boy suffering from acute otitis media. As he had previously experienced a rash after the administration of a penicillin, the medication order was swit...

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Publicado en:Journal of Clinical Pharmacy & Therapeutics Vol. 25; no. 3; pp. 161 - 165
Autores principales: Falconer CL, Gardner DM
Formato: case study Journal Article
Publicado: Wiley-Blackwell Jun2000
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Treatment of acute otitis media in patients with a reported penicillin allergy.
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          Falconer CL
          Gardner DM
      sug:
        subj:
          Drug Hypersensitivity Prevention and Control
          Otitis Media Drug Therapy
          Trimethoprim-Sulfamethoxazole Combination Therapeutic Use
          Acute Disease
          Child
          Clinical Trials
          Male
          Penicillins Adverse Effects
          Penicillins Therapeutic Use
          Trimethoprim-Sulfamethoxazole Combination Adverse Effects
          Child: 6-12 years
          Male
      ab: Otitis media occurs commonly in children, and is usually treated with an antibiotic. In this case report, amoxicillin was prescribed for a 6-year-old boy suffering from acute otitis media. As he had previously experienced a rash after the administration of a penicillin, the medication order was switched from amoxicillin to trimethoprim/sulfamethoxazole (TMP/SMX). In an effort to determine whether or not this intervention was appropriate, references were found using Medline, International Pharmaceutical Abstracts and the Cochrane Library. Issues to be addressed included the need for antibiotics in acute otitis media, the comparative efficacy and tolerability of antimicrobial agents and the reliability of reported penicillin allergies. Amoxicillin and TMP/SMX were found to be first-line agents in the treatment of acute otitis media owing to their efficacy, safety and cost, with neither drug being significantly better than the other. The need to treat otitis media with antibiotics remains controversial. Reported penicillin allergies were found to be an unreliable indicator of a potentially serious reaction. In conclusion, it was found that treatment with TMP/SMX was an appropriate intervention.
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        Journal Article
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    language: English
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