Parotid salivary immunoglobulins, recurrent respiratory tract infections and gingival health in institutionalized and non-institutionalized subjects with Down's syndrome.

BACKGROUND: The purpose of the present study was to evaluate the possible correlation between recurrent respiratory infections (RRIs), gingival health and the secretion rates of salivary immunoglobulins (Igs) in institutionalized (I) and non-institutionalized (NI) individuals with Down's syndrome (D...

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Publicado en:Journal of Intellectual Disability Research Vol. 47; no. 2; pp. 101 - 108
Autores principales: Chaushu S, Nof EY, Becker A, Shapira J, Chaushu G
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Feb2003
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2003
      vid: 47
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        106852004
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        10.1046/j.1365-2788.2003.00446.x
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        atl: Parotid salivary immunoglobulins, recurrent respiratory tract infections and gingival health in institutionalized and non-institutionalized subjects with Down's syndrome.
      aug:
        au:
          Chaushu S
          Nof EY
          Becker A
          Shapira J
          Chaushu G
        affil: Clinical Lecturer, Department of Orthodontics, Hebrew University-Hadassah School of Dental Medicine, PO Box 12272, Jerusalem 91120, Israel; drshaush@netvision.net.il
      sug:
        subj:
          Down Syndrome
          Gingivitis Complications
          Gingivitis Complications
          Immunoglobulins
          Parotid Gland
          Respiratory Tract Infections Complications
          Respiratory Tract Infections Complications
          Adolescence
          Adult
          Child
          Convenience Sample
          Correlational Studies
          Descriptive Statistics
          Funding Source
          Israel
          Kruskal-Wallis Test
          Saliva Analysis
          Wilcoxon Rank Sum Test
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Child: 6-12 years
      ab: BACKGROUND: The purpose of the present study was to evaluate the possible correlation between recurrent respiratory infections (RRIs), gingival health and the secretion rates of salivary immunoglobulins (Igs) in institutionalized (I) and non-institutionalized (NI) individuals with Down's syndrome (DS). METHODS: Stimulated parotid saliva was collected from nine I and 14 NI subjects with DS. Salivary flow rate, secretion rates of total salivary IgM, IgG and IgA, and the incidence of RRIs were determined. Gingival health was recorded by using the plaque index, the gingival index and the percentage of bleeding surfaces (BS). RESULTS: The mean salivary flow rate and parotid Ig secretion rates in the I group were 25% of those of the NI group. The prevalence of RRIs in the I group was more than twice that in the NI group. Oral hygiene and gingival health were significantly better in the NI group. CONCLUSIONS: The lower parotid Ig secretion rates in I individuals with DS might be a possible factor involved in their susceptibility to recurrent infections compared to NI subjects with DS.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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