Heart rate turbulence in Chagas disease.
Heart rate turbulence (HRT) quantifies the biphasic response of the sinus node to ventricular premature complexes (VPCs) and is a powerful electrocardiogram related risk predictor. VPCs are frequent in Chagas disease, a potentially lethal illness, and can hamper the analysis by conventional methods...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 26; no. 1; pp. 406 - 411 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jan2003
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106879028&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106879028 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Jan2003 vid: 26 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 106879028 106879028 2003138263 106879028 ppf: 406 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Heart rate turbulence in Chagas disease. aug: au: Ribeiro ALP Schmidt G Sousa MR Lombardi F Gomes MED Perez AA Barros MVL Machado FS Rocha MOC sug: subj: Chronobiology Disorders Etiology Heart Rate Trypanosomiasis Physiopathology Adult Analysis of Covariance Analysis of Variance Autonomic Nervous System Brazil Chi Square Test Descriptive Statistics Electrocardiography Female Male Multiple Linear Regression Post Hoc Analysis Premature Ventricular Contractions Complications Spearman's Rank Correlation Coefficient Ventricular Ejection Fraction Human Adult: 19-44 years Female Male ab: Heart rate turbulence (HRT) quantifies the biphasic response of the sinus node to ventricular premature complexes (VPCs) and is a powerful electrocardiogram related risk predictor. VPCs are frequent in Chagas disease, a potentially lethal illness, and can hamper the analysis by conventional methods of autonomic heart control. The aim of the study was to examine HRT in patients with Chagas disease. Chagas disease patients and healthy controls (group 0, n = 11) without other diseases were submitted to a standardized protocol, including electrocardiogram, echocardiography, and 24-hour Holter monitoring. Chagas disease patients were divided according to their left ventricular systolic function: normal (group 1, n = 103) and reduced ejection fraction (group 2, n = 23). Two HRT indices, turbulence onset (TO) and turbulence slope (TS), were calculated and compared among groups after adjustment for covariates like the prevalence of VPCs and the mean heart rate. Chagas disease patients had significantly altered TO (group 1: -0.0186, group 2: -0.0126) and TS (group 1: 10.844, group 2: 7.870) values in comparison with controls (TO -0.0256, TS 19.829); P < 0.001 for both comparisons. In conclusion, HRT data may be useful in the electrocardiographic analysis of autonomic heart control in Chagas disease. Its prognostic value remains to be determined. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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