Limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infants.

We determined the validity of the carbon 13-labeled urea breath test in young children. We found that although the 13C-labeled urea breath test had a specificity greater than 90%, borderline or false positive results occurred more frequently in children younger than 2 years compared with older child...

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Publicado en:Journal of Pediatrics Vol. 139; no. 5; pp. 734 - 738
Autores principales: Imrie C, Rowland M, Bourke B, Drumm B
Formato: research tables/charts Journal Article
Publicado: Elsevier B.V. 2001 Nov
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2001 Nov
      vid: 139
      iid: 5
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      pub: Elsevier B.V.
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        10.1067/mpd.2001.118398
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        atl: Limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infants.
      aug:
        au:
          Imrie C
          Rowland M
          Bourke B
          Drumm B
        affil: Department of Paediatrics, Conway Institute of Molecular and Biomedical Research, University College, Dublin, Ireland
      sug:
        subj:
          Helicobacter Infections In Infancy and Childhood
          Breath Tests In Infancy and Childhood
          False Positive Results In Infancy and Childhood
          Convenience Sample
          Prospective Studies
          Descriptive Statistics
          Sensitivity and Specificity
          Infant
          Child, Preschool
          Male
          Female
          Funding Source
          Human
          Infant: 1-23 months
          Child, Preschool: 2-5 years
          Male
          Female
      ab: We determined the validity of the carbon 13-labeled urea breath test in young children. We found that although the 13C-labeled urea breath test had a specificity greater than 90%, borderline or false positive results occurred more frequently in children younger than 2 years compared with older children. False positive results may be caused by oral-urease-producing organisms because direct intragastric administration of 13C urea reduced the excess delta 13CO2. Care is urged in interpreting one positive 13C-labeled urea breath test in children younger than 2 years.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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