Balancing recruitment and protection: children as research subjects.

Since 1994, federal guidelines for research in the United States have called for the inclusion of special populations, among them, children, in clinical research (National Institutes of Health, 1998). While the guidelines are intended to assure the fair distribution of research benefits to children,...

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Publicado en:Issues in Comprehensive Pediatric Nursing Vol. 24; no. 4; pp. 241 - 252
Autores principales: Meaux JB, Bell PL
Formato: tables/charts Journal Article
Publicado: Taylor & Francis Ltd Oct-Dec2001
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Taylor & Francis Ltd
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        atl: Balancing recruitment and protection: children as research subjects.
      aug:
        au:
          Meaux JB
          Bell PL
        affil: University of Central Arkansas, 201 Donaghey Ave, Dept of Nursing, Conway, AR 72035
      sug:
        subj:
          Protection of Human Subjects
          Research Subject Recruitment In Infancy and Childhood
          Clinical Trials
          Consent (Research) In Infancy and Childhood
          Research Ethics
          United States
          Consent (Research) Legislation and Jurisprudence
          Legislation
          Age Factors
          Infant
          Child, Preschool
          Child
          Adolescence
          Infant: 1-23 months
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Adolescent: 13-18 years
      ab: Since 1994, federal guidelines for research in the United States have called for the inclusion of special populations, among them, children, in clinical research (National Institutes of Health, 1998). While the guidelines are intended to assure the fair distribution of research benefits to children, this federal mandate has created an ethical dilemma for researchers. Health professionals involved in research with children are called on to balance improving access and recruitment of children for clinical trials with the need to protect this very vulnerable population. Given this balancing act, it is important for nurse-researchers to be familiar with the issues of informed consent and assent with children. Our article reviews instances of exploitation of children in research, laws and federal regulations on informed consent and assent designed to protect children, and research on factors that affect children's capacity to consent/assent. We conclude with recommendations to assure a proper balance between the need to recruit children into clinical trials and the need to protect their rights as human subjects.
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      ougenre: Article
    language: English
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