Pyoderma gangrenosum: signpost of underlying disease.

Pyoderma gangrenosum lesions often arise as small pustules that rapidly expand into large, deep ulcers. Generally, this skin disorder is identified on the basis of its characteristic appearance; there are no tests or pathognomonic histopathologic features that routinely confirm the diagnosis. The go...

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Publicado en:Consultant (00107069) Vol. 42; no. 4; pp. 457 - 460
Autor principal: Zuber TJ
Formato: Journal Article
Publicado: HMP Global 2002 Apr 1
Acceso en línea:Ver este registro en EBSCOhost
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      pub: HMP Global
      place: Malvern, Pennsylvania
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        atl: Pyoderma gangrenosum: signpost of underlying disease.
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        au: Zuber TJ
        affil: Associate, Department of Family and Preventive Medicine, Goizueta Business School and Rollins School of Public Health, Emory University, Atlanta
      sug:
        subj:
          Skin Diseases Etiology
          Ulcer Etiology
          Necrosis Etiology
          Chronic Disease Complications
      ab: Pyoderma gangrenosum lesions often arise as small pustules that rapidly expand into large, deep ulcers. Generally, this skin disorder is identified on the basis of its characteristic appearance; there are no tests or pathognomonic histopathologic features that routinely confirm the diagnosis. The goal of laboratory testing is to exclude other disorders or to identify underlying diseases. Treatment can be difficult; it may take many months for the lesions to resolve. Dressings, compresses, rest, and washing with hydrogen peroxide promote reepithelialization. Topical or intralesional corticosteroids are most helpful for patients with early disease. Systemic corticosteroids are the mainstay of therapy; other options include immunosuppressive and antileprosy drugs.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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