Changes in explicit memory associated with early dementia in adults with Down's syndrome.
BACKGROUND: A modified version of the Selective Reminding Test (SRT) (Buschke 1973) was used to examine the changes in memory that occur with early-stage dementia of the Alzheimer's type (DAT) in adults with intellectual disability (ID) and Down's syndrome (DS), and to compare these changes to those...
| Publicado en: | Journal of Intellectual Disability Research Vol. 46; no. 3; pp. 198 - 209 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Mar2002
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106933061&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106933061 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09642633 EUL jtl: Journal of Intellectual Disability Research issn: 09642633 maglogo: Y pubinfo: dt: Mar2002 vid: 46 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 106933061 106933061 2002064848 10.1046/j.1365-2788.2002.00365.x 106933061 ppf: 198 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Changes in explicit memory associated with early dementia in adults with Down's syndrome. aug: au: Krinsky-McHale SJ Devenny DA Silverman WP affil: New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York 10314-6399: sjmchale@worldnet.att.net sug: subj: Intellectual Disability Memory Disorders Down Syndrome Dementia Funding Source Prospective Studies Neuropsychological Tests Research Subject Recruitment Data Analysis, Statistical Sensitivity and Specificity Male Female Human Male Female ab: BACKGROUND: A modified version of the Selective Reminding Test (SRT) (Buschke 1973) was used to examine the changes in memory that occur with early-stage dementia of the Alzheimer's type (DAT) in adults with intellectual disability (ID) and Down's syndrome (DS), and to compare these changes to those occurring with 'normal' ageing. METHOD: Hierarchical linear modelling analyses showed steep declines in the performance of participants who had met the criteria for the onset of DAT. Non-demented participants also showed declines in performance which were related to their age. However, the absolute magnitude of these declines was consistent with a 'normal' ageing pattern and not with undetected dementia. RESULTS: In analysing the specific memory components that are compromised, the present authors found that participants with early-stage DAT showed severely diminished long-term storage and retrieval processing abilities compared to their non-demented peers. Notably, these declines preceded other symptoms of dementia, in most cases by more than a full year and sometimes by as much as 3 years. CONCLUSIONS: Thus, the present results clearly confirm that memory processes are affected during early dementia in adults with DS, and that the SRT has promise as a clinical tool. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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