Regression of MALT lymphomas coexisting in the duodenal bulb and the stomach by eradication of Helicobacter pylori.
We report the regression of coexisting mucosa-associated lymphoid tissue (MALT) lymphomas in the duodenal bulb and gastric corpus brought about by Helicobacter pylori eradication. During an endoscopic examination, multiple polyps in the duodenal bulb were observed in a 62-year-old woman. The patholo...
| Publicado en: | Journal of Gastroenterology Vol. 37; no. 4; pp. 288 - 293 |
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| Autores principales: | , , , , , , , , , |
| Formato: | case study pictorial Journal Article |
| Publicado: |
Springer Nature
2002
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106974264&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106974264 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09441174 EJ7 jtl: Journal of Gastroenterology issn: 09441174 maglogo: N pubinfo: dt: 2002 vid: 37 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 106974264 NLM11993513 2002151474 10.1007/s005350200037 NLM11993513 106974264 ppf: 288 ppct: 5 formats: tig: atl: Regression of MALT lymphomas coexisting in the duodenal bulb and the stomach by eradication of Helicobacter pylori. aug: au: Hori K Nishigami T Chiba T Matsushima Y Kojima T Hori, Kimiyuki Nishigami, Takashi Chiba, Tsutomu Matsushima, Yumi Kojima, Takane affil: Hori Gastro-Intestinal Surgery Clinic, Noguchi, Kakogawa, Japan sug: subj: Lymphoma Etiology Helicobacter Pylori Helicobacter Infections Complications Helicobacter Infections Drug Therapy Disease Remission Duodenal Neoplasms Etiology Japan Endoscopy Biopsy Lymphoma Familial and Genetic Duodenal Neoplasms Familial and Genetic Antiulcer Agents Administration and Dosage Amoxicillin Administration and Dosage Clarithromycin Administration and Dosage Middle Age Female Middle Aged: 45-64 years Female ab: We report the regression of coexisting mucosa-associated lymphoid tissue (MALT) lymphomas in the duodenal bulb and gastric corpus brought about by Helicobacter pylori eradication. During an endoscopic examination, multiple polyps in the duodenal bulb were observed in a 62-year-old woman. The pathology of the duodenal polyps was low-grade B-cell MALT lymphoma. Gastric MALT lymphoma was also detected in biopsies of rough mucosa from the gastric corpus. Southern blot analysis showed rearranged bands of DNA immunoglobulin heavy chain J portion (IgH-J) in both lesions, but the positions of these bands were different in the two lesions. H. pylori was recognized in the gastric mucosa by positive serum H. pylori antibody and urease tests, while bacterial bodies were not found in the duodenal bulb. With 1 year after the successful eradication of H. pylori, both the lesions, that in the duodenal bulb and that in the gastric corpus, had disappeared. Furthermore, positive rearrangement of IgH-J was not found at either of the lesion sites. In May 2000, 3 years after the treatment, endoscopic surveillance failed to find any recurrence of these malignant lymphomas. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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